Live Cell Beating Assay Using Human iPSC-derived Cardiomyocytes for Evaluation of Drug Efficacy and Toxicity
Poster Oct 05, 2011
Oksana Sirenko, Carole Crittenden, Blake Anson, Jayne Hesley, Yen-Wen Chen, Nick Callamaras and Evan F. Cromwell
Derived from human induced pluripotent cells and highly purified, iCell® Cardiomyocytes are especially attractive because they express ion channels and demonstrate beating and action potentials similar to primary cardiac cells.
The work in this poster demonstrates cell based assays for measuring the impact of pharmacological compounds on the rate and magnitude of beating cardiomyocytes with different instrument platforms.
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