qPCRas a primary screen in drug discovery
Poster Sep 15, 2008
We report the use of qPCR technique to follow the thermal unfolding of proteins by the binding of the dye SYPRO Orange, and exploit its potential as a robust and high-throughput primary screen for small molecule drug discovery.
Comparison of the Biological Effects of Long-Term Exposure of Human Bronchial Epithelial Cells to Total Particulate Matter from 3R4F Cigarette Smoke or Aerosol from the Candidate Modified Risk Tobacco Product (cMRTP) THS2.2Poster
We mimicked chronic exposure in smokers’ airways by continuously exposing BEAS-2B cells to TPM from 3R4F cigarette smoke or aerosol of the Tobacco Heating System 2.2 (THS2.2), a cMRTP, for 12 weeks.READ MORE
Genomic Analysis of L5178Y tk+/- Cells and their Induced tk-/- Mutant ColoniesPoster
The goal of this pilot study was to exploit NGS technology with a view to shedding new light on the genome of cells used in the MLA, as well as the changes induced as a result of the exposure to mutagens.READ MORE