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Accelerating Process Optimization in a Busy Chemical Development Lab

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The new Reactor-Ready Lab Reactor from Radleys, UK provides an immediate benefit to a busy process development lab.

Researchers at a leading US pharmaceutical company have recently invested in Reactor-Ready for use in their chemical development lab. The process R&D group, specializing in small molecule research are using Reactor-Ready for optimizing new or existing chemistry, identifying and eliminating impurities, and screening processing variables for transfer to kilo-labs, pilot plant and manufacturing sites.

Commenting on their existing methods the Lead Scientist said, “We use round bottom flasks, but temperature control via mantles or oil baths is poor. Alternatively, when we use traditional jacketed reactor vessels, we need a different set up for every scale change. Even changing a reactor of the same size takes ages.”

“So I liked Reactor-Ready the minute I saw how easy it was to change reactors. Reactor-Ready does it all. I get one stand which fits all sizes up to 5 litres. I get overhead stirring on all scales. I get vacuum jacketed vessels, which provide excellent temperature control with minimum heat loss, which is a real advantage at low temperatures, and I get the ability to rapidly change out my reactors.”

“The first time I changed vessels, it took about 5 minutes but now I can change in less than 2 minutes. That includes removing and attaching the heating fluid hoses. Occasionally I lose a drop or two of heat transfer fluid but most times I lose none. The thing I like about the system is the control and speed. I get better control of my reactions and I can vary my work or scale immediately”.