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Agilent’s New 1200 Infinity Liquid Chromatography Series Offers Productivity and Affordability


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Agilent Technologies Inc. has announced the 1200 Infinity Series, setting new levels of performance in analytical HPLC and UHPLC. The 1200 Infinity Series includes the new Agilent 1220 Infinity LC, the new Agilent 1260 Infinity LC and the enhanced Agilent 1290 Infinity LC.

The 1200 Infinity Series portfolio offers integration of column technology, instrumentation and software to ensure utmost productivity. The 1220 and 1260 Infinity LCs offer enhanced HPLC and RRLC performance at an HPLC price. All 1220 and 1260 Infinity systems are standardized on 600 bar system pressure, 80 Hz data-acquisition speed and 2x or 10x higher UV sensitivity.

The 1220 and 1260 Infinity LCs are 100 percent compatible with HPLC methods, ensuring risk-free replacement or upgrades of existing 1100 or 1200 Series instruments. Further, the new 1260 Infinity Quaternary Bio-inert LC system offers high performance in bio-analysis and bio-purification.

“We ended the UHPLC debate with last year’s introduction of the Agilent 1290 Infinity LC," said Patrick Kaltenbach, Agilent’s vice president and general manager, Liquid Phase Separations Business. "Now we are raising the HPLC standard with a new portfolio that offers a unique continuum of future-proof HPLC, RRLC and UHPLC solutions to match any application or budget.”

The Agilent 1200 Infinity Series portfolio allows customers to tailor the exact systems they need, from the simplest manual isocratic LC through the high performance sensitive UHPLC systems. The power range of 1200 Infinity Series LC systems is fully compatible with the latest column technology, such as 600 bar Poroshell and Zorbax RRHT or 1200 bar Zorbax RRHD columns.

Agilent 1220 Infinity LC

The 1220 Infinity LC is an integrated and easy-to-use system for routine HPLC and advanced RRLC analyzes, providing maximum return on investment. The 1220 Infinity LC offers a 600 bar power range at up to 5 mL/min and up to 10 mL/min at lower pressure, an 80 Hz detector speed and is fully compatible with all additional detectors within the 1200 Infinity Series, as well as with Agilent 6100 Series Single Quadrupole LC/MS Systems. Besides being capable of running RRLC applications, the 1220 Infinity can run existing conventional HPLC methods. The 1220 Infinity LC offers superior Agilent quality and utilizes 1260 or even 1290 Infinity LC technology and parts.

Agilent 1260 Infinity LC

The 1260 Infinity LC offers rapid resolution power, pushing RRLC performance to new limits. The power range of the 1260 Infinity Isocratic and Quaternary Pump of 600 bar at 5 mL/min and up to 10 mL/min at lower pressure handles 3.0 and 4.6 mm id columns with sub-2-micron or superficially porous particles used in new Poroshell columns. The 1260 Infinity Binary LC uses high-pressure solvent mixing for superior gradient accuracy at 600 bar and up to 5 mL/min and allows lower delay volumes, making it well suited for narrow bore columns.

Further, the new 1260 Infinity Diode Array Detector increases UV sensitivity by 10-fold allowing accurate peak detection and integration.

Full HPLC and RRLC compatibility enables unchanged execution of existing methods while being prepared for transfer to modern columns technologies whenever required. The 1260 Infinity Quaternary LC is also available as a 100 percent bio-inert version with widest, 1-14 pH-range. All 1260 Infinity LC systems are priced similarly to earlier 1200 Series HPLC systems.
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