AnaSpec Introduces FRET Technology Brochure

AnaSpec has developed a broad portfolio of products based on fluorescence energy transfer (FRET) technology, most notably the SensoLyte™ line of high-performance assay kits. Showcasing this technology, AnaSpec has announced the availability of its new FRET Technology Brochure.

According to AnaSpec, the detection of proteases and screening of specific protease inhibitors are critical factors in the discovery of potential drugs for the treatment and management of protease-related diseases. In the last decade or so, the use of fluorescence resonance energy transfer (FRET) technology has made the continuous assay of protease activity and high throughput screening (HTS) of protease inhibitors faster and easier.

AnaSpec’s SensoLyte™ line offers collection of long wavelength protease assay kits. Combining proprietary FRET technologies with world-class peptide expertise, the SensoLyte™ family demonstrates significant performance over traditional assay kits.

The perfect overlap of absorption and emission spectrums of the SensoLyte™ FRET pairs allows for a level of sensitivity that is as much as 40x greater, the company says.

AnaSpec’s newly-released FRET Technology Brochure features:

• SensoLyte™ protease assay kits for HTS of inhibitors or quantitation of HCV, HIV, MMPs, a and b-Secretases, Renin, TACE, ACE2, & WNV.

• Table of the different donor and acceptor molecules.

• Listing of dye-labeled amino acids or resins that can be used as building blocks.

• Concise guideline on how to design FRET peptides.