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Biotage® Introduces EVOLUTE® WCX: Now Providing a Total Solution for Basic Compounds

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Biotage, a supplier of tools and technology for medicinal and analytical chemistry, has announced the further expansion of its family of products with the launch of Evolute WCX. The announcement was made at the 2010 Pittcon in Orlando, Florida USA.

“This is the second expansion of the EVOLUTE family of resin-based, solid-phase extraction products, demonstrating our continued commitment to delivering high-quality solutions to our customers” says Scott Carr, Vice President of Commercial Operations for Biotage.

EVOLUTE WCX is a mixed-mode weak cation exchanger, developed for extraction of strongly basic analytes and quaternary amines from aqueous samples. These analytes are typically found in pesticides and provide analytical scientists with the ability to extract pesticides from diverse matrices, ranging from ground water to blood samples.

The resin-based sorbent is surface modified with well defined hydroxyl-functional oligomers, imparting excellent water wettability. An optimized combination of non-polar (hydrophobic), polar (hydrophilic) and cation exchange interactions allows efficient extraction of strongly basic analytes of wide ranging polarities and quaternary amines, allowing for up to 50% more efficient recoveries of pesticide residues. The non-polar/cation exchange dual retention mechanism allows the use of a rigorous interference regime, providing extremely clean extracts and reducing matrix effects associated with LC-MS/MS analysis.