Carl Zeiss Launches Laser Scanning Microscope LSM 5 DUO

Carl Zeiss has announced the launch of LSM 5 DUO laser scanning microscope. The LSM 5 DUO combines two award-winning confocal laser scanning microscopes, the LSM 510 META and LSM 5 LIVE, to form a single instrument that establishes a benchmark for experimental and imaging versatility.

The fast line scanning module of the LSM 5 LIVE and point scanning module of the LSM 510 META, both winners of the R&D 100 Award, are integrated in the workstation. 

The two independent scanner groups provide flexibility in optical sample micromanipulation for FLIP or FRAP applications or when utilizing photoactivateable and photoconvertible variants of fluorescent proteins.

Dynamic processes up to the kHz range may be observed using the system's ultra-fast acquisition capabilities.

"This groundbreaking combination of high resolution, sensitivity, speed and spectral imaging is an essential pre-requisite for the next generation of live cell imaging research. LSM 5 DUO makes that possible now," says Aubrey Lambert, Carl Zeiss UK.

Carl Zeiss claims that, the LSM 5 DUO is ideally suited to a wide range of live cell imaging applications, allowing researchers to probe deeper into the cell's molecular processes.

Developmental studies can be carried out at high speed and in 3-D resolution, even with low-magnification lenses. Physiological measurements can be perfectly matched to biological timescales or spectral properties.

The META detector is designed to enable fluorochromes with overlapping emission spectra to be separated using its Emission Fingerprinting technology. 

Photomanipulation experiments involving pixel-precise laser irradiation, e.g. FRAP, FLIP, FLAP, photo-activation or -conversion and uncaging, can be conducted at high-resolution timescales.

And, ultra-quick 4-D image acquisition enables dynamic structures to be monitored simultaneously.