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FEI Introduces Vitrobot Mark IV

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FEI has introduced the next generation of its Vitrobot™ cryo sample preparation tool, the Vitrobot Mark IV.

According to company, the Mark IV is a system that features a newly-designed touchscreen user interface operated under a Linux operating system and robotics that ensures reproducible freezing of samples. Automated transfer from the vitrification medium into the liquid nitrogen atmosphere offers consistent and higher yield sample throughput.

Three-dimensional transmission electron microscopy (TEM) visualization of macromolecular structures and molecular machines in their native hydrated state has become a critical tool for structural biologists focusing on interactive biological and biochemical processes at the macromolecular level.

The Vitrobot is a high-throughput tool designed to enable the physical fixation of biological structures within ultra-thin vitrified ice layers so samples can withstand the high voltages used in TEMs long enough to acquire the necessary image.

Beyond biological applications, the Vitrobot Mark IV can also be used for pharmaceutical, food and a variety of general industrial applications where colloidal structures need to be characterized and analyzed.

FEI will feature the Vitrobot Mark IV at the 26th Annual Meeting of the American Society for Virology, July 15-17, 2007 at Oregon State University in Corvallis, Ore. and at the Microscopy and Microanalysis meeting August 6-9, 2007 in Fort Lauderdale, Fla.