Inpharmatica Extends Admensa Interactive™ Drug Discovery Tools
Product News Mar 20, 2006
Inpharmatica Ltd. has released some editions of Admensa Interactive™, its compound optimisation platform, including compound prioritisation tools and an in silico suite of predictive drug absorption, distribution, metabolism and excretion models.
These editions respond to market demands for tools that group together even more effectively key elements of compound optimisation.
The versions of Admensa Interactive now available for on-site installation are;
- ADME Edition: includes a range of rigorously validated high throughput ADME QSAR models for desktop installation,
- P450 Edition: designed to provide quantum based models predicting sites of P450 metabolism on chemical compounds,
- Professional Edition: combines both the ADME QSAR and P450 quantum models for complete virtual ADME optimisation.
Inpharmatica claims that, the intuitive Admensa Interactive interface can objectively evaluate extensive libraries of structures and compare individual compounds, based on a wide range of compound properties, either virtual or synthesised, to aid effective decision making.
Data from experiments or users' own in-house models can be incorporated in this environment. Users can manipulate individual compound structures in real-time to explore individual ADME properties or overall compound quality.
Admensa Interactive is an integral component of Inpharmatica's gene-to-candidate technology platform which integrates biology- and chemistry-based drug discovery activities.
This platform is designed to optimize target selection based on druggability, and enables rapid identification of hits and selection of high quality leads and pre-clinical candidates, which are prioritized on the basis of good drug-like characteristics and clinical indication.
Commenting on the release, John Lisle, Inpharmatica's CEO, said, "These new editions of Admensa Interactive are a direct response to user feedback on one of our most successful offerings."
"We expect these enhancements both to provide even better solutions for our pharmaceutical and biotechnology customers' discovery needs, and to reinforce Inpharmatica's leading position in the marketplace."