Lipid Analysis for Early Stages of Drug Discovery

Customer Reference Flagship Ventures: Lipid analysis for early stages of drug discovery

Lipotype performed lipid analysis for Flagship VentureLabs with the aim to better understand molecular compositions of chondrisomes, pharmaceutically active derivatives of mitochondria. The research of Flagship VentureLabs is on novel ways of preparation of chondrisomes that have bene cial structural characteristics, yield, concentration, stability, viability, integrity, or function. The lipidomic results facilitated the characterization of isolated chondrisomes in order to evaluate their quality and subsequently were used to le a recently published patent application. Further details are available here.

Applications of Lipidomics in drug discovery include mode-of-action studies, target validation, effect of delivery system on lipid metabolism, biomarker identification.