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Low Volume SPE Assays Enhanced by C18 Sorbent

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Porvair Sciences Ltd. has announced the availability of a new range of BioVyon™ C18 silica columns and microplates for use in low volume Solid Phase Extraction (SPE) assays.

Packed bed SPE columns and microplates traditionally perform relatively inefficiently when using the shallow sorbent beds necessary to get good recovery from smaller sample volumes.

By immobilizing the C18 sorbent within the porous BioVyon polymer - Porvair have created high surface area matrix that provides control of flow rate. Further the immobilized C18 sorbent cannot form liquid channels and does not require inert frits to support it thereby minimizing hold-up volume. The combination of these attributes has enabled Porvair to introduce a new range of SPE columns and microplates that provide consistency.

BioVyon C18 is initially being offered in 96-well microplates as a 10mg per well loading suitable for low volume bioassay preparation and clean-ups. In the popular 1ml cartridge format, BioVyon C18 is available in a choice of 12.5, 25 and 50mg loadings.