New FTS SMART Freeze Dryer™ Technology from SP Scientific
Product News May 27, 2010
FTS SMART Freeze Dryer™ technology from SP Scientific, is a control software tool developed to enable development scientists to accelerate the task of developing and optimizing freeze drying cycles.
Based upon control algorithms developed by leading lyophilisation experts - SMART Freeze Dryer technology is available exclusively for the SP Scientific LyoStar™ and Process Development freeze dryer ranges.
SMART Freeze Dryer Technology enhances freeze dry cycle development in several important ways. Traditional cycle development relies on the experience and intuition of the development scientist, along with a trial and error approach. This often requires weeks of development time, and multiple test cycles can consume scarce and valuable active ingredients.
SMART technology enables the developer to generate the right cycle on the first attempt. Due to the trial-and-error approach used in conventional freeze-dry cycle development, it is common practice for scientists to build-in "safety factors" in their cycles to ensure product integrity. By adding this safety margin, it is estimated that most production lyophilisation cycles are excessively long, often by several days.
SMART Freeze Dryer technology allows the development scientist to create a streamlined but safe cycle that can shave days off the production cycle. This efficiency gain can eliminate production bottlenecks, expand capacity and reduce production costs.
Data analysis on traditional freeze-drying cycles requires careful sampling and hours of detailed calculations by an experienced freeze-drying scientist. SMART technology features a feedback loop that provides detailed data on the pharmaceutical product and the freeze-drying process, including product resistance, heat flow and product thickness. Ready-access to such data can enhance scale-up efforts, provides a data trail for regulatory compliance, and frees-up valuable scientist time for other tasks.