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Exclusive! BromoTag® Degrader for Target Exploration and Validation
BromoTag® AGB1 is our new TAG Degrader licensed exclusively to Bio-Techne by the University of Dundee. TAG Degraders are valuable tools for validating targets and use a targeted protein degradation approach that is generalizable to any intracellular target protein.
To facilitate your experiments, we also offer the negative control (BromoTag® cis-AGB1, Cat. No. 7687) and the antibody for detection of BromoTag AGB1-induced degradation of fusion proteins.
Key Features of BromoTag® AGB1
• Highly selective and potent "Bump & Hole" TAG Degrader (DC50, 6h < 15nM)
• Recruits VHL to selectively degrade proteins tagged with the mutant BromoTag domain, Brd4BD2 L387A
• Suitable for in vitro and in vivo applications
BromoTag® is a registered trademark of the University of Dundee and is used under license.