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i-Ome® Discovery: Precision Platform for Antibody Biomarker Discovery
Credit: Sengenics
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i-Ome™ Discovery: Precision Platform for Antibody Biomarker Discovery

i-Ome™ Discovery: Precision Platform for Antibody Biomarker Discovery
Credit: Sengenics

i-Ome Discovery is Sengenics’ most advanced protein microarray, meticulously designed for antibody and autoantibody profiling in biomarker discovery. This powerful platform delivers key insights into immune responses to disease and identifies targetable biomarkers for drug and vaccine development, including disease-associated protein antigens, pathogenic antibodies, and protective antibodies. In addition to its primary focus, i-Ome Discovery can also be used to study protein-protein and small molecule-protein interactions, expanding its applications to broader areas of research.


What makes i-Ome Discovery unique is its use of full-length, correctly folded proteins, enabled by proprietary KREX technology. By preserving native conformational epitopes recognized by 90% of humoral antibodies, it delivers biologically meaningful results. With a false discovery rate (FDR) of less than 1%, you can focus on actionable insights without wasting time on misleading data.


The platform features 1800+ human protein antigens—expertly curated by immunologists and representing diverse protein functions and disease areas. Renowned for exceptional sensitivity, reproducibility, and a linear range across 4 logs, i-Ome Discovery detects subtle yet distinct signals that stand out clearly against background noise. It also supports simultaneous analysis of up to two antibody isotypes, delivering greater depth and breadth of understanding into disease pathways and mechanisms.


You can access i-Ome Discovery directly through Sengenics or our global network of certified service providers and distributors. We provide end-to-end support—from experimental design to data analysis—ensuring a seamless experience tailored to your needs.


Elevate your research with i-Ome Discovery. Unlock the answers that matter most—with precision, reliability, and unmatched clarity.


Note: KREX™ technology, including i-Ome™ Discovery, is now part of the SomaScan™ suite of proteomic solutions offered by Standard BioTools.


Product Specifications
Product Type Protein Microarray
Applications Antibody and autoantibody profiling, protein-protein interactions, small molecule-protein interactions (Research use only)
Format Full-length, correctly folded proteins immobilized on a non-denaturing glass slide
Species Human
Array Proteins 1800+
Sample Types Serum and Plasma (EDTA, citrate). Custom analysis may be available for other sample types.
Sample Volume < 50 μL
Antibody Isotypes Single or dual isotype screening (IgG, IgA, IgM)
Replicate Spots 4 per protein