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bit.bio

bit.bio is an award-winning human synthetic biology company whose mission is to code cells for novel cures. They have developed an end-to-end platform for the creation of any human cell type. With their cutting-edge and patent-protected opti-ox precision cell programing technology, bit.bio can deterministically program human induced pluripotent stem cells (iPSCs) into a chosen cell identity with unprecedented biological consistency at an industrial scale and approximately 10 times faster than conventional methods. Their platform has the potential to unlock a new generation of medicines.

Latest bit.bio Content

Webinar - Neurodegenerative Disease
Webinar

Human iPSC-Based Models of Glial Cells for Studying Neurodegenerative Disease

The increasing implication of glial cells in neurodegenerative diseases makes them an appealing addition to iPSC-based model systems for investigating disease mechanisms.
Collection of mammalian cells derived from brain tissue on a black background. Astrocytes have been stained green, nuclei have been stained red (neurons) and blue (all cells).
Industry Insight

Exploring Human iPSC-Derived Astrocytes for Advancing CNS Research

In this interview, Dr. Mitzy Rios de Anda sheds light on the potential of human iPSC-derived astrocytes, discussing how these cells are reshaping our understanding of the brain, neurological diseases and therapeutic development.
TMI10 image
Video

Leveraging Human iPSC-Derived Astrocytes for Neurological Research and Therapy

In this episode we speak with bit.bio about astrocytes and how bit.bio's innovative technology is transforming research in this area.
Images of the two speakers sit underneath the webinar title. To one side, red-labelled cells are shown.
Webinar

Powering a New Generation of Physiologically-Relevant CRISPR Screens

On-Demand
CRISPR-Cas9 gene editing is an essential functional genomics tool, facilitating the cataloging of genomic variations linked to human diseases for the discovery and validation of novel drug targets.
iPSC-derived astrocytes, human astrocytes, glial cells, opti-ox technology
Product
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ioAstrocytes - Human iPSC-Derived Astrocytes

ioAstrocytes offer a solution to researchers who are searching for easy-to-use, highly characterised human cells that are designed for co-culture and effectively recapitulate astrocyte functions within CNS models in vitro
Microscopic view of fluorescently labeled cells showing green cell bodies with blue nuclei connected by thin, bridge-like structures
App Note / Case Study

Studying the Link Between Cell Migration and Neurodegenerative Disease With iPSC-derived Microglia

In this application note, researchers from Medicines Discovery Catapult (MDC) evaluated the suitability of iPSC-derived microglia as a model for studying the mechanics of microglia activation, shedding light on their role in neurodegeneration and the potential for therapeutic targets.
A doctor writing on a clipboard next to a brain, examining medical records and analyzing brain functions
App Note / Case Study

Improving Physiological Relevance in Neurological Disease Drug Development

This case study explores the use of human iPSC-derived microglial cells as a more reliable model for neurobiological drug development.
Colorful pattern of DNA strands interwoven in a complex structure
Poster

Improving Physiological Relevance in Functional Genomics Screens

This poster describes the use of CRISPR-ready iPSCs, which are engineered to constitutively express Cas9, enabling the rapid generation of high-efficiency gene knockouts and CRISPR screens in a functional, physiologically relevant cell background.
TMI10
Video

How To Accelerate Research and Drug Discovery in Motor Neuron Disease: A Deep Dive Into Precision Reprogrammed Human iPSC-Derived Motor Neurons

In the Teach Me in 10 video, Dr. Marcos Herrera-Vaquero, bit.bio discusses motor neurons and their critical role in Motor Neuron Diseases (MNDs) such as amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA).
Neuro Research
App Note / Case Study

Speeding Up Neuroscience Research

Delve into this case study to explore how a research lab at King’s College London used hiPSC-derived neurons to shed light on synaptic biology and potential treatments for psychiatric conditions.
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