Biomarkers – News and Features

This article explores how epigenetic mechanisms control gene expression, how their disruption drives cancer and how targeting these processes is reshaping cancer diagnosis and treatment.

Researchers have found that AKI is triggered by fatty molecules called ceramides, which cause serious injury by damaging kidney mitochondria.

Researchers link platelet activity in midlife to Alzheimer’s brain markers, suggesting a simple blood test could predict risk.

New research comparing four different flu vaccines found that the ability of the vaccines to activate cells of the immune system that help to protect against infection varied greatly depending on the vaccine type and age of the patient.

Scientists have created a blood test to guide more effective ovarian cancer treatment, by identifying the women more likely to respond to an ovarian cancer treatment known as PARP inhibitor therapy.

Scientists from the Human Protein Atlas created a pan-disease blood atlas that maps thousands of proteins across 59 diseases and over 8,000 people. The study reveals distinct protein fingerprints for each condition.

German researchers studying tuberculosis that spreads beyond the lungs identified unique immune patterns in patients’ blood. These patterns reveal how the body fights the infection and could lead to a simple blood test to replace biopsies.

Single-cell RNA sequencing identified distinct immune profiles in extrapulmonary TB, linking interferon–IL-1 signaling to disease progression and paving the way for blood-based diagnostics.

New study reveals a structural association between circulating microclots and neutrophil extracellular traps (NETs) in patients with long COVID.

Long COVID in women is linked to gut leakiness, chronic inflammation and reduced testosterone, pointing to biological causes of sex-specific symptom severity.