Cell Signaling – Multimedia
Poster
Comparison of Key Signaling Pathways in Lung Cancer Cells Grown in 2D and 3D Formats
Evaluation of Wnt/ß-catenin and BMP pathway proteins and gene expression in NSCLC cell lines A549 and H460 in 2D and 3D cultures.
App Note / Case Study
Characterization of Protein-Protein Interactions using Triple Detection Size Exclusion Chromatography (SEC-TD)
In this application note, triple detection size exclusion chromatography (SEC-TD) is used to understand the ability of proteins to form ordered, structured complexes. The controlling mechanism behind these protein complexes is fundamental to our knowledge of protein signaling pathways and the physiological responses they control.
Poster
Targeting Cancer Stem Cell-Related miRNAs for Prostate Cancer Therapy
The poster focuses on the pivotal function of miRNAs in tumorigenesis by regulation of self renewal and apoptosis via cancer stem cell signalling pathways with special focus on their regulation of Epithelial to Mesenchymal transition in metastatic prostate cancer.
Poster
Expression of Wnt5a in Urothelial Carcinoma as a Potential Prognostic Marker
Our results support the previous studies that suggest Wnt5a plays a pathological role in urothelial carcinoma.
Poster
Validation of a Novel Tumoroid-Based Cell Culture Model to Perform 3D in vitro Cell Signaling Analyses
Here we demonstrate an in vitro HTRF® microplate assay that can quantify total, as well as phosphorylated elF4E.
Poster
Developing Functional Monoclonal Antibodies for Beta-3 Adrenergic Receptor
Our preliminary data showed that several mAb clones specific ally bound to the receptor while increasing the receptor function by acting as agonists.
Poster
Exploring the Therapeutic Potential of a Peptide Derived from a Poxviral Immune Evasion Protein
•9R-VIPER is an effective at TLR4 and TLR2 signal inhibition than VIPER.
•The structure of 9R-VIPER and the mutant peptide L6AE10A were investigated by NMR.
•Important structural information was uncovered and an explanation was found for the loss
of activity when important residues are changed.
•The structure of 9R-VIPER and the mutant peptide L6AE10A were investigated by NMR.
•Important structural information was uncovered and an explanation was found for the loss
of activity when important residues are changed.
App Note / Case Study
Efficient washing of magnetic beads
The use of magnetic beads as the solid phase in a multiplexed ELISA enables high throughput cytokine screening and offers several advantages over common ELISA assays with direct coupling of the analyte to the well-surface.
Poster
Automation of a Novel Cell-Based ELISA for Cell Signaling Pathway Analysis
Monitoring and quantifying cell signaling pathways is critical for understanding the behavior of cell processes and many disease states. Monitoring and quantifying cell signaling pathways is critical for understanding the behavior of cell processes and many disease states.
App Note / Case Study
BD Cytometric Bead Array Cell Signaling Flex Set System
The BD™ Cytometric Bead Array (CBA) Cell Signaling Flex Set
system lets you achieve high productivity in cell signaling studies
by extracting more data from less sample faster than traditional
Western blot techniques.
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