CRISPR and Genome Editing – News and Features

Functional genomics can help deconvolute the link between genotype and phenotype in disease, revealing new drug targets and progressing understanding of existing drugs.

A study by Georgia Tech researchers finds that bacteria maintain species cohesion through homologous recombination, a form of frequent and random DNA exchange. This process keeps microbial species genetically cohesive.

This article explores how broadly neutralizing antibodies are being researched, not only for their potential in the prevention of HIV, but also for other rapidly mutating viruses such as influenza and SARS-CoV-2.

Macquarie University researchers and an international team have completed the first synthetic yeast genome, a breakthrough in synthetic biology. This achievement includes a novel tRNA neochromosome.

Molecular editing could transform waste plastic upcycling to produce new macromolecules.

Researchers revealed that the rotavirus NSP4 protein drives disease severity by disrupting calcium signaling in infected and nearby cells. These disruptions worsen symptoms and trigger immune responses.

Researchers explored the role of the TLE6 protein in male fertility using a novel mouse model. TLE6 deficiency caused significant reductions in sperm count and motility and led to abnormal sperm morphology.

A new type of off-the-shelf cell-based immunotherapy shows promise for B-cell lymphomas, and could make make future cellular immunotherapies less expensive and more accessible.

Technology Networks spoke with Dr. Thomas Dennison, University of Cambridge, to learn more about the advantages of using patient-derived organoids for modeling inflammatory bowel disease (IBD).

Researchers have developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, autoimmune diseases and much more.