Drug Targets – News and Features
News
Pancreatic Cancer Protein Targeted by Protein Degraders
University of California, Riverside scientists have designed novel agents that bind to and degrade Pin1, a protein linked to pancreatic cancer. These “molecular crowbars” destabilize Pin1, making it vulnerable to degradation.
News
Microglia Exacerbate Damage in APOE4 Model of Alzheimer’s
New research shows that microglia, which usually clear debris, cause harmful inflammation in the presence of APOE4 protein.
News
New Clusters of Cells Identified in the Human Amygdala
Scientists at UC Davis discovered new gene expression clusters in the amygdala of humans and non-human primates, enhancing understanding of emotional disorders. This research may open pathways for developing targeted therapies for anxiety.
News
Experimental Drug Triggers Rapid Cell Death in Cancer Models
Researchers have designed a small molecule that holds promise as a cancer therapeutic, activating the apoptosis cascade in tumor cells while sparing healthy cells.
Article
Reclaiming the Narrative for Black Scientists
This article highlights several inspiring men and women working across academia and industry who are breaking barriers and regaining ownership of their own narratives.
News
Cancer Risk Linked to “Guardian of the Genome” in Ulcerative Colitis
Researchers have shed new light on the role of p53 in the pathogenesis of ulcerative colitis, which is linked to an increased colon cancer risk.
News
Experimental Cancer Drug Suppresses Breast Cancer Bone Metastases
In a new study, the drug RK-33 has demonstrated promise in treating breast cancer that has spread to the bone (breast cancer bone metastasis). RK-33 was previously shown to help treat other types of cancer and viral illnesses.
News
Diabetes-Linked DNA Changes Disrupt Pancreatic Cells’ Stress Resilience
Research identifies how DNA sequence changes linked to diabetes risk affect pancreatic cell stress responses. The study shows that stressors like inflammation and high blood sugar can overwhelm insulin-producing cells.
Industry Insight
Getting New Drug Modalities to Market: How Can Your Data Strategy Help?
This article explores the revolution in new drug modalities and the challenges around effective data strategies to support AI efforts.
Industry Insight
Innovation Award Winner Announced at ELRIG Drug Discovery 2024
Technology Networks had the pleasure of speaking with the ELRIG Innovation Award Winner Constructive Bio’s CEO, Dr. Ola Wlodek, to discuss its award-winning innovations and learn more about its mission.
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