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Exosomes – News and Features

A scientist places blood test vials into a rack.

Blood Test Could Identify Individuals at Risk of Developing Parkinson’s Disease

A newly developed blood test could identify the pathology that triggers Parkinson's disease before symptoms occur, allowing clinicians to screen those at high risk of the disease.
A neuron.

Why Tackling Neurodegeneration Requires Global Partnerships

Neurodegenerative diseases are characterized by synapse dysfunction and the aggregation of proteins in the brain, which ultimately lead to neuronal loss. This article will review the studies and methods powering our growing understanding of the mechanisms behind neurodegenerative disease.
Cancer immunotherapy. A white cancer cell is attacked by two small red T cells.

Improved mRNA Therapy Enhances Glioblastoma Response to Immunotherapy

Researchers have loaded extracellular vesicles with therapeutic mRNA, and shown how they can be used to enhance immunotherapy responses in glioblastoma.
Stem cells.

Fitness of Cells Used in Cell Transplants Improved

Researchers found exposing cells to a small molecule drug improved their fitness during hematopoietic stem cell transplants, which could broaden access and improve outcomes for ex vivo gene therapy.
A diagram of a uterus.

Stem Cell-Derived Components May Treat Underlying Causes of PCOS

Polycystic ovarian syndrome (PCOS) affects millions of women and is notoriously difficult to treat. A new treatment has been unveiled that may improve multiple PCOS symptoms.
Blue cells labelled with green and red dyes.

New Insights Into Cause of Poor Wound Healing in Diabetics

Defective exosomes, which shuttle signals between cells, can drive inflammation and impair wound healing in diabetic patients, according to a new study.
A cell dividing.

How Do Extracellular Vesicles Impact Human Health?

Researchers wanted to understand how cells react to these extracellular vesicles (EVs) produced by different cell types and at varying concentrations.
Double helix structure of DNA.

Ancient Genes Could Affect the Development of Neurodegeneration

It has been suspected for some time that viral infections contribute to the genesis and development of neurodegenerative diseases. Laboratory studies now suggest a mechanism that does not require infection by external pathogens.
Inside of an extracellular vesicle.
Industry Insight

Building the Future of Extracellular Vesicle Isolation

Hans van der Voorn tells us about some of the recent progress in the extracellular vesicle-based diagnostics and therapeutics landscape, particularly the need for industrial-scale EV isolation workflows.
A mouldy strawberry and tomato.

How Fungi Use Lipid “Bubbles” To Infect Plants

Researchers have found a way to defeat mold without showering toxic chemicals on the crops.