High-Throughput Screening – News and Features

Scientists at the North Carolina State University found that a chemical compound produced through the digestion of a common artificial sweetener causes damage to DNA.

A ground-breaking study has led to the development of a small molecule probe that could improve our understanding of an important cellular messenger.

This article explores the various screening technologies used in the development of therapeutic antibodies and outlines the recent advances in this area.

Researchers in Japan identify a compound that can prevent cisplatin-induced renal toxicity and improve the outcomes of cancer treatment.

Technology Networks had the pleasure of speaking with Walid A. Houry, professor of biochemistry at the University of Toronto, to find out about the discovery of compounds that can induce protease hyperactivation to kill cancer cells.

Despite approved treatments being available, multiple myeloma remains incurable, but researchers aimed to improve treatment outcomes by testing hundreds of existing therapeutics to predict their effectiveness.

At SLAS 2023, Technology Networks spoke with the PerkinElmer Life Sciences and Diagnostics organization to discuss the launch of two new automated platforms. These innovative systems are designed to improve workflows such as high-throughput drug discovery screening and next-generation sequencing library prep through advances in automation technologies.

A new high-throughput screening model has been developed to assess potential drug compounds to treat cervical cancer.

Researchers have identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of an inherited disease that often results in severe visual impairment or blindness in early childhood.

This article will discuss the principles of fragment-based drug discovery and will highlight some examples of recent successes in this area.