High-Throughput Screening – News and Features

Fourier transform infrared spectroscopy is a hugely popular technique today. In this article, we consider what it is, how it works, how to interpret the data and its many applications.

This article will discuss advances in fragment-based drug discovery and will highlight some examples of recent successes in this area.

Researchers have demonstrated that a novel targeted therapy could be an effective treatment option for neuroblastoma, a deadly pediatric cancer.

A new research study has explored a large library of authorized drugs to identify compounds that may elicit antiviral activity against SARS-CoV-2. An antibiotic, clofoctol, produced promising results in a mouse model.

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In this article, we will discuss how the use of different high-throughput screening methods can help to accelerate the drug discovery process.

This article introduces the fundamentals of electrophysiological investigation by describing the ionic basis of action potentials and the different electrophysiological techniques used to explore and understand excitable tissues and organs.

According to research, statins, which are prescribed as cholesterol-lowering drugs, inhibit the expression of a metastasis-associated gene in tumor cells.

Dr. Alice Soragni and colleagues at UCLA are using organoids to study diseases and possible treatments. In their latest study, the team developed clinically-relevant, personalized models to find therapeutics for chordoma, a rare bone cancer.

Combining antiviral drugs with different mechanisms of action has been shown to inhibit SARS-CoV-2 replication in mice and in human lung cells.