LC-MS – Multimedia

This application note explores how the latest LC/MS technology can be used to confidently quantify nitrosamine impurities for the development of safer, more effective drugs.

This poster highlights the latest spatial biology solutions for GBM tissue analysis, offering critical insights into the metabolic signatures and immune cell infiltration of this tissue type.

The mobile phase is a fundamental component of LC-MS analysis, influencing analyte separation, ionization, chromatographic resolution, sensitivity and overall method performance.

With this poster, dive into the world of mass spectrometry troubleshooting, and discover detailed tables listing the accurate mass of elements, organic solvents and potential contaminant ions.

Per- and polyfluorinated alkyl substances (PFAS) are used in a broad range of consumer goods. Due to their extreme stability, they accumulate in the environment and organisms, posing a significant threat to human health. Hence, proper monitoring of PFAS is required to help mitigate these harmful effects.

Bile acids are well known for their roles in cholesterol homeostasis, lipid absorption and as metabolic signaling molecules. They are implicated in a variety of disease states and therefore serve as an exciting focus on research in novel biomarker discovery.

This poster compilation outlines the latest LC-MS/MS and QTOF MS methods for accurate environmental monitoring.

Identifying novel biomarkers with bottom-up proteomics remains a substantial challenge due to the wide concentration ranges and potentially low abundance of important analytes.

Stringent safety requirements associated with the analyses of carcinogenic and mutagenic impurities can present significant challenges. Methods must achieve a high level of sensitivity and selectivity while maintaining sufficient sample throughput.

Custom oligo synthesis can result in the formation of impurities. Hence, final products must be characterized to ensure they meet quality assurance and control standards.