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Single-Cell Analysis – News and Features

Human cells.
Article

The Need To Scale Single-Cell Functional Studies

Kathrin Herbst reviews the pros and cons of various single-cell technologies and discusses the need to move to functional readouts in the future.
Cancer cells.
News

New Study Reveals Targetable Mechanism in Pancreatic Cancer Metastasis

A research paper published in Nature Cancer details new insights into the role of efferocytosis – the burying of dead cells – in pancreatic cancer that spreads to the liver.
Cancer cells.
News

Targeting Chemotherapy-Resistant Cells

Each round of chemotherapy kills the majority of cancer cells, while a small population of them survives through treatment. These cells are typically more resistant for the next cycle of therapy and can thus regrow.
Double helix structure of DNA.
News

Single-Cell Analysis Explains Cancer Patients' Sensitivity to Epigenetic Drugs

Researchers described the effects of chemotherapy at the single cell resolution in the bone marrow of Myelodysplastic Syndrome patients. The results help better understand which cellular populations are more sensitive to an epigenetic drug.
A woman holding her pregnant bump.
News

Genetic and Cellular Changes Pinpointed in Placenta Accreta

A new study may change the way clinicians and scientists understand, diagnose and treat placenta accreta spectrum disorder, a serious condition in which the placenta fails to separate from the uterus at birth.
A plastic model of a kidney held in a person's hand.
News

Six Novel Urine Biomarkers Discovered for Active Renal Lupus

Six proteins found in urine have been identified as biomarkers for lupus nephritis, which may help the early identification of renal involvement in lupus.
Cancer cells.
News

Non-Cancerous Cells May Help Predict Prostate Cancer Spread

Non-cancerous cells called stromal cells may be useful in assessing these tumors’ potential to spread, and may even be targets for future prostate cancer treatments
A birthday cake with 100 candles on.
News

More People Are Living to 100 Than Ever Before

New data from the UK’s Office for National Statistics (ONS) estimates that 15,120 centenarians were living in England and Wales in 2022, a 3.7% increase from 2021.
Cells.
News

Scientists Create a Single-Cell Atlas of the Human Placenta During Labor

During childbirth, numerous physiological and cellular transformations take place in both the mother and infant. Scientists have created a single-cell atlas of the human placenta during labor.
Stem cells.
News

Mapping the Genome of Oral Stem Cells Holds Hope for Regenerative Medicine

Comparisons of two stem cell populations from extracted wisdom teeth demonstrates significant differences in the cells’ differentiation potential.
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