Single-Cell Analysis – News and Features

Researchers developed Spacia, a computer model that improves detection of cell-to-cell communication (CCC) using spatially resolved transcriptomics data. Spacia, which uses multi-instance learning, provides deeper insights into diseases.

A study reveals that aberrant activation of the MYC oncoprotein drives significant changes in the prostate cancer microenvironment. Researchers found MYC's role in transforming the tissue from inflammatory to immunosuppressive.

For the first time, researchers have developed a spatiotemporal map of malaria infection in the liver, a key site for vaccine targeting.

Scientists at the University of Vienna have identified potential multipotent stem cells in the sea anemone Nematostella vectensis. These cells, regulated by ancient conserved genes, allow the anemone to regenerate and potentially avoid aging.

Researchers at Washington University School of Medicine in St. Louis describe the dramatic changes within nerve cells that make regeneration possible. Such findings could inspire the development of new therapies for spinal cord injuries in people.

Researchers at the Icahn School of Medicine have shown that stress inhibits vagus nerve stimulation of the glands of Brunner, which compromises beneficial gut bacteria populations and host immunity.

Strokes lead to irreversible damage to the brain. As the cellular reactions to a cerebral infarction are not yet fully understood, there is a lack of possible approaches to promote the regeneration of damaged nerve tissue in the brain

In this interview, we spoke to Jason Koth, product management lead at Scale Biosciences, to learn more about their new ScalePlex technology for leveraging and overcoming current limitations within single-cell genomics.

A new small molecule could alleviate pain for sickle cell disease patients who don't respond to hydroxyurea.

Researchers have identified a previously unknown cause of long COVID within the lungs. Their study suggests that a treatment previously used for rheumatoid arthritis might be effective in halting the chronic inflammation associated with the condition.