Spatial Biology – News and Features

Researchers have used generative AI to design new mitochondrial targeting sequences (MTSs), addressing the current shortage of reliable tags for mitochondrial delivery. Such sequences could have application in metabolic engineering and therapeutics.

In this interview, Dr. Elizabeth Neumann discusses her journey into science, her research utilizing single-cell analysis and her commitment to mentorship and advocacy.

A newly published study involving researchers from Karolinska Institutet indicates that prostate cancer can be diagnosed at an early stage through a simple urine sample.

A new computational method brings an ecology-inspired lens to tissue analysis, offering a pipeline to interpret spatial omics data to understand disease progression.

A new study from researchers at Moffitt Cancer Center shows that blocking a chemical process called nitrosylation could make one of the most aggressive forms of melanoma more treatable.

The tumor microenvironment is a harsh environment where metabolic adaptations are key. In this article, we explore how the metabolic constraints of the TME influence cancer and immune cells and dive into the metabolic cross-talk between them.

Mapping a tumor's cellular neighborhood in three dimensions could identify potential targets for personalized cancer therapy.

Researchers have discovered that expansion of mutant blood cells, a phenomenon linked to ageing, can be found in cancerous tumours, and this is associated with worse outcomes for patients.

A team of researchers from the University of Chicago, has identified a novel oncometabolite that accumulates in tumors and impairs immune cells’ ability to fight cancer.

New research demonstrates the role of the Galectin-1 protein in the nucleus of the cells surrounding the tumor-fibroblasts contributing to their activation.