Spatial Biology – News and Features

Researchers from the VIB-KU Leuven Center for Cancer Biology, in collaboration with other scientists, have discovered a way to enhance the immune system's ability to fight cancer by reprogramming T-cell metabolism.

The more Western foods, the more glycogen in the cancer cells, the bigger and worse the tumor growth.

Researchers from Mayo Clinic have identified specific proteins — fibronectin and smooth muscle actin — within colorectal cancer tissues that are associated with resistance to immunotherapy treatment.

Analyzing donated brains from deceased people with Alzheimer’s disease who received amyloid-beta immunization, researchers found that when these treatments work, the brain’s immune cells help to restore a healthier brain environment.

Immuno-oncology and cell-based treatments, which harness the body's own immune system to combat illnesses like cancer, have emerged as some of the most promising areas of study. This article explores how cell therapy is evolving.

Colorectal cancer and pancreatic ductal adenocarcinoma that harbored the KRAS G12C mutation often carried other genetic alterations that can be associated with resistance to KRAS G12C inhibitors.

New research has uncovered a mechanism by which brain cancer cells reprogram immune cells from fighting cancer to enabling tumor growth.

A deep-learning framework can support spatial transcriptomics techniques by integrating gene expression, spatial data and histological images to advance tissue analysis.

While controlling swelling caused by brain cancer is important, a new study shows that a commonly prescribed anti-swelling drug suppresses the immune system for weeks after dosage, inhibiting the body’s ability to fight the cancer.

Researchers find four coordinated gene expression programs in immune cells from glioma tumors, including two that could lead to immunotherapy resistance.