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Spatial Biology – News and Features

Cells dividing.
News

How Stem Cell Embryo Models Won Method of the Year

A collection of ingenious biological tools for studying the genesis of life has been awarded Nature Methods’ coveted Method of the Year award for 2023
Cells.
News

Alzheimer's May Be Driven by “Exhausted” Immune Cells

New research demonstrates that microglia, the immune cells of the brain, wither away as Alzheimer’s takes hold in both mice and humans, and that APOE4, a key gene variant implicated in Alzheimer’s, may mediate these changes.
AI written on a computer chip.
News

AI Tool Interprets Cancer Imaging With “Unprecedented Clarity”

Penn Medicine researchers developed an artificial intelligence tool to quickly analyze gene activities in medical images and provide single-cell insight into diseases in tissues and tissue microenvironments.
A healthcare worker tends to a patient receiving treatment in the hospital.
Article

Improving Cancer Patient Care With Professor Mark Lawler

Precision medicine and immunotherapy have the potential to revolutionize cancer treatment, but challenges must be addressed to ensure their smooth integration into clinical practice.
A strand of RNA.
Article

Exploring the Latest Advances in Transcriptomics

This article explores the latest technologies currently in use for transcriptomic research. It also highlights the latest advancements in transcriptomics technology, focusing on single-cell, spatiotemporal and the “dark-transcriptome”.
A zebrafish.
News

Atlas of Zebrafish Development Created

Researchers published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development.
Brain cells highlighted in red.
News

Full Atlas of the Mammalian Brain Reveals Unique Structure of Ancient Regions

A world-first cell atlas has opened a window into the complexity of the mammalian brain. The map details more than 5,000 cell-type clusters in the mouse brain and marks out their location.
Cells.
News

Immune Cells Shape Lungs Before Birth

Healthy lung development hinges on immune-epithelial crosstalk, revealing a new role for immune cells outside of immunity, with implications for treating respiratory diseases.
Cancer cells.
News

Researchers Identify Pathway From Breast Cancer to Brain Metastasis

Moffitt Cancer Center researchers are working to better understand the molecular mechanisms that promote the development and progression of breast cancer brain metastasis to help improve diagnostics and treatments.
A plastic model of one hemisphere of the brain, with a brain cell beside it.
News

Innovative Method Identifies Rare Brain Cell Types

Researchers have used single-cell sequencing to identify every cell in a system, revealing new brain cell subtypes and enabling detailed research into brain changes in Alzheimer's.
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