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Drug Discovery

Drug Discovery

Featured Videos

Human Body and Media Solutions

Do you wish to improve your drug discovery experimental setup? Ever wonder how to improve on cell line data. Explore your options with primary cells from multiple organs of the human body. Make the right choices for drug discovery.

Role of Sulfotransferases in Drug Metabolism and Potential for Drug Drug Interactions

Continuing our series on non-CYP-mediated metabolism pathways, we will be discussing another of the most requested enzymes: Sulfotransferases (SULTs). SULTs participate in Phase 2 metabolism of xenobiotics in humans and are characterized by the abundance and broad tissue distribution of the enzymes. Gene regulation and genetic polymorphism of SULTs also contribute to our understanding of the significance of these enzymes in the process of drug development.

Latest Videos

Interfering Peptides Targeting Protein-Protein Interactions

Katja Arndt, University of Potsdam, speaking at Discovery Chemistry Congress 2015.

Detecting Single DNA Molecules with Optical Microcavities

Frank Vollmer discusses a technique using a single DNA oligonucleotide receptor and to follow its successive interactions with DNA molecules in a sample solution.

Highly-integrated Lab-on-a-chip System for Multiparameter Analysis at the Point-of-care

A lab-on-a-chip system called the "Fraunhofer ivD-platform" has been established which opens up the possibility for an on-site analysis at low costs.

The Application of a Resonant Coil Magnetometer for Point of Care Diagnostic Applications

Richard Luxton, University of the West of England, speaking at Point of Care Diagnostics 2015

From Batch to Continuous Flow Processing: Development of Safe and Improved Methods for Aerobic Oxidation

Alain Favre-Reguillon, University of Lyon, speaking at Flow Chemistry India 2015

15 Years HCS: Next Gen Screening Devices Learn from Each Other. Literally. Fast Workflow Development & BigData Image Analytics Used to be a Challenge. What’s Next?

Reducing development times and maintenance cost is now easier than ever if we integrate existing technologies from other disciplines.

High-Throughput Approaches to Cell Biology

Robin Ketteler, University College London, discusses high throughput screening of autophagy using siRNA and small molecule compounds.

Discovery of Potent and Selective Inhibitors of Monopolar Spindle 1 (MPS1) Kinase

This talk presents the discovery and optimization of potent and selective MPS1 inhibitors based on the 1H-pyrrolo[3,2-c]pyridine scaffold, guided by structure-based design and cellular characterization of MPS1 inhibition.

Selection of Label-free Cellular Imaging Applications for their Integration in the Screening Strategy

Gerardo Turcatti, Ecole Polytechnique Federale De Lausanne, speaking at Screening Europe 2015.

Fragment-based Approach to Multi-target Compounds

The presented work deals with the development of a fragment based strategy for dual-target drug discovery.

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