ADMET in Drug Discovery With Dr. Andrew Mtewa
In this Teach Me in 10 episode, we are joined by Dr. Andrew Mtewa, senior lecturer in chemistry at the Malawi University of Science and Technology.
Mtewa discusses the properties that make a molecule a potential drug candidate worthy of pursuing, factors that help improve drug absorption and drug distribution in the body as well as the role of metabolism on drug action and rates.
Andrew Mtewa suggests the resources below for further reading:
•https://www.nature.com/articles/nrd1032
• https://www.sciencedirect.com/science/article/abs/pii/S1056871900001076?via%3Dihub
• https://www.sciencedirect.com/science/article/abs/pii/S1359644618303301
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350845/