Design, Validation and Evaluation of a Bioaffinity based Flow-biochemistry Device

Video   Jun 01, 2016

 

About the Speaker
András Guttman holds the Translational Glycomics Professorship at the Horváth Csaba Laboratory of Bioseparation Sciences (University of Debrecen, Hungary) and leads the application efforts at Sciex (Brea, CA) and. His work is focusing on capillary electrophoresis and CE-MS based proteomics and glycomics analysis of biopharmaceutical, biomedical and cell biology interests. Dr Guttman previously held academic appointments at Northeastern University (Boston, MA) and a Marie Curie Chair at University of Innsbruck (Austria) as well as industrial positions at Novartis (La Jolla, CA), Genetic BioSystems (San Diego, CA), and Beckman Instruments (Fullerton, CA), developing high resolution capillary electrophoresis and microfluidics based separation methods. Professor Guttman has more than 269 scientific publications, wrote 35 book chapters, edited 4 textbooks and holds 19 patents. Until recently he served on the CASSS Board and as president of the Hungarian Chapter of the American Chemical Society. He is on the editorial boards of numerous international scientific journals. Dr. Guttman graduated from University of Veszprem, Hungary in chemical engineering, where he also received his doctoral degree. He was recognized by the Analytical Chemistry Award of the Hungarian Chemical Society in 2000, elected as a member of the Hungarian Academy of Sciences in 2004, named as Fulbright Scholar in 2012, received the CASSS CE Pharm Award in 2013, the Arany Janos medal of the Hungarian Academy of Sciences, the Pro Scientia award of the University and the Dennis Gabor Award of the Novofer Foundation in 2014.
AbstractFlow-biochemistry utilizes continuous flow biochemical devices for biocatalysis, biotransformation and biochemical interaction based flow-analytical systems. Design of flow-biochemistry based rare cell capture systems was supported by computational fluid dynamics modeling. Trajectories of yeast cell movement were followed under a microscope and compared with the modeling results. Melanoma cells were used to evaluate the efficiency of the cell capture capability of the bioaffinity based flow-biochemistry microdevice.

 
 
 
 

Recommended Videos

Blood, Rats and Anticoagulants: The Story of Warfarin

Video

The history of warfarin, one of the earliest anticoagulant drugs, is littered with the bodies of sick cows and poisoned rats. This animation tells the story of how a bloody beginning gave rise to a life-saving medication.

WATCH NOW

Introduction to Peptides and Proteins for Bioanalysis Using LC-MS

Video

Khalid Khan, Senior Manager Business Development, discusses the basic structure of amino acids, peptides, and proteins, including specific examples like monoclonal antibodies. The ionization and fragmentation of peptides and how they differ from small molecules is also discussed.

WATCH NOW

Solutions for High-Throughput and Phenotypic Screening

Video

Accelerate drug discovery workflows with state-of-the art imaging and detection instruments, assay technologies, reagents, versatile automation systems, and powerful informatics solutions that work together to ensure consistent, accurate, physiologically relevant results. Wrest more meaning from your findings with PerkinElmer's one-of-a-kind analytics, and amplify your phenotypic or target-based screens to identify hits and lead compounds in small and focused or high-throughput volumes.

WATCH NOW

 

Comments | 0 ADD COMMENT

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE