How does a medicine get from the lab to patients?

Antibiotics are losing their effectiveness, threatening to make common infections deadly. Is the future of medicine lurking in Iceland's icy waters?

Komodo dragons, the largest lizards on earth, carry antimicrobial peptides in their blood as a defense against infections. Researchers at George Mason University used these peptides to treat wound infections in mice and hope we will be able to develop new antibiotics based on these chemicals.

PLOS author John Ioannidis, Professor of Medicine, of Health Research and Policy, and of Statistics at Stanford University, considers how the scientific community can move toward greater truth in published research.