We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Regulation of antibody immunotherapy by fine-tuning FcR interactions

Video   Apr 22, 2013

 

About the Speaker


Mark Cragg is a Professor in Experimental Cancer Biology at the Cancer Sciences Division of Southampton University School of Medicine, UK. He obtained his PhD in 1998 and did his postdoctoral studies with Martin Glennie in Southampton and then Andreas Strasser at the Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia. He has published over 60 papers, many in high impact journals such as the Journal of Clinical Investigation, PNAS, Plos Medicine and Blood and leads a dynamic research group interested in all aspects of how therapeutics such as antibodies result in tumour regression and how they can be improved.
Abstract

Monoclonal antibodies (mAb) represent a growing class of ‘block-buster’ cancer drugs and so understanding of their modes of action is critical. Here, we present evidence that different mAb interact with Fc receptors differently in order to achieve their therapeutic activities.

 
 
 
 

Recommended Videos

Plug-and-play Paperfluidic Diagnostics

Video

Researchers at MIT have developed half-inch modular blocks that can be constructed to produced different diagnostic devices. They hope that their low-cost, easy-to-assemble half-inch creations will soon land in the hands of many small laboratories around the world, to improve infection detection and monitoring.

WATCH NOW

On the Pathway to Discovery, All Signals are Clear

Video

What if you could get high quality results without the hassle? Our wide range of assay solutions makes it easier to take an orthogonal approach to your cell-based assays, glean more biologically relevant information, and get to breakthroughs faster.

WATCH NOW

John Ioannidis on Moving Toward Truth in Scientific Research

Video

PLOS author John Ioannidis, Professor of Medicine, of Health Research and Policy, and of Statistics at Stanford University, considers how the scientific community can move toward greater truth in published research.

WATCH NOW

 

Like what you just watched? You can find similar content on the communities below.

Cancer Research Immunology & Microbiology

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE