Explore the science of why mixing drugs and drug interactions with other substances can lead to dangerous health complications.
Which of the following is risky behavior: a person taking cholesterol medicine with grapefruit juice? Or a person taking Acetaminophen before going out for drinks? Or a person on blood thinners who takes an aspirin? Turns out, all of them are risky. Each has inadvertently created a drug interaction that could lead to serious complications. Céline Valéry describes the dangers of mixing substances.
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It is important to identify the enzymes that significantly contribute to the metabolism of a drug candidate and to evaluate the potential of a drug candidate to be a victim or perpetrator. Knowing how a drug candidate is eliminated by the human body is important in understanding the potential for drug-drug interactions.
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