We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Advertisement

Utilizing hiPSC-Derived Neurons and Cardiomyocytes For Drug Screening

Video   Oct 18, 2016

 

Patient specific induced pluripotent stem cells (iPSC) complement traditional cell-based assays used in drug discovery and could aid in the development of clinically useful compounds. They allow interrogation of differentiated features of human cells not reflected by immortalized lines, and importantly they carry disease-specific traits in complex genetic backgrounds that can impact disease phenotypes. Development of technology platforms to perform compound screens of iPSC with relatively high-throughput will be essential to realize their potential for disease modeling and drug discovery. Towards this goal, we have been working to develop a standardized battery of assays against which iPSC-derived neurons can be screened for specific phenotypes. We will discuss our screening results and development of patient cell specific and hiPSC based models for testing of drugs on disease relevant cell types.

 
 
 
Advertisement
 

Recommended Videos


Stem cell biology: EVOS™ M5000 microscope at the cutting edge research

Video

Quickly check that staining has worked or the reporter line is expressing the protein of interest.

WATCH NOW

Liver regeneration: EVOS™ M5000 microscope at the cutting-edge research

Video

Perform an entire timecourse in the tissue culture suite and avoid making regular trips to the confocal.

WATCH NOW

 

Like what you just watched? You can find similar content on the communities below.

Cell Science

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE