Genomic tools for Psilocybe cubensis propagation
Kevin McKernan, CSO at Medicinal Genomics will be joining us to discuss genetic variation in the Psilocybe cubensis synthesis pathway and the design of qPCR assays for simultaneous quantification of E. coli and Salmonella species contamination concurrent with Psilocybe cubensis species identification.
Exploiting the timsTOF and MALDI-2 Platforms to Assess Pharmacodynamics and Pharmacokinetics in Preclinical Models
An integrated evaluation of the pharmacodynamic and pharmacokinetic properties of a drug is essential for successful translation to the clinic. However, cost-effective methods to measure these parameters at the systems level in pre-clinical models are lacking. Here, we introduce a timsTOF and MALDI-2 workflow to evaluate therapeutic activity. The platform combines ion mobility, mass spectrometry-based imaging, absolute drug quantitation across different biological matrices, in vivo isotope tracing, and global metabolome analysis in the adult zebrafish.
Predictive Toxicology: Organ-Chips Demonstrate Superior Performance to Animal Models and Spheroids
To explore how this challenge might be approached, 780 human Liver-Chips were analyzed to determine their ability to predict drug-induced liver injury caused by small molecules.
Innovations in Disease Modeling 2022
This inaugural online symposium will explore the tools and techniques being used to study diseases in the lab. Focus will be given to cell culture, organ-on-a-chip and organoid models, as well as, how innovations are enabling researchers to elucidate the underlying biological mechanisms of disease and support diagnostic and therapeutic development.
The Analytical Landscape of Cannabis Testing Session 4: Residual Solvents & Terpenes by GC-MS
In the first part of this webinar, Kirk will talk about headspace sampling and GC-MS measurement of residual solvents using the JEOL JMS-Q1500GC quadrupole GC-MS system, and how the technique can meet California’s minimum reporting limits.
Protein Biomarker Models for Oncology Risk Assessment and Treatment Monitoring
In this webinar you will learn how the power of large-scale proteomics can be leveraged for multiple divergent applications in the field of oncology.