CRISPR-Cas9 gene editing is an essential functional genomics tool, facilitating the cataloging of genomic variations linked to human diseases for the discovery and validation of novel drug targets.

This webinar highlights innovative solutions to these challenges, Ebru Selin Sele offers her insights into advanced methodologies for more efficient and accurate metabolite identification.

From selecting instrumentation, building a team, managing day to day operations and helping to shape the future of the organization you work for, running a lab presents many challenges. Leadership experts will provide practical tips and guidance for current and aspiring lab managers working in industry and academia.

In recent past respiratory seasons, the world witnessed a “tripledemic” of Influenza (flu), SARS-CoV-2 (COVID-19), and Respiratory Syncytial Virus (RSV). The 2024-25 landscape will likely be different, with new virus variants, new vaccines and treatments, like the game-changing antibody that protects children from RSV. The healthcare and public health community have also learned some valuable lessons going forward with the ever-evolving respiratory agents.

In this presentation, Dr. Rodney Rohde will discuss the primary microbiology, epidemiology, control, prevention, vulnerable populations, the importance of laboratory validation, and the benefits of molecular-based testing of these three primary respiratory season pathogens.

Advances in monoclonal antibody (mAb) engineering have led to additional challenges in the purification of these modalities, including high levels of aggregates. Ion exchange chromatography is often not sufficient to achieve purity targets meaning hydrophobic interaction chromatography (HIC) and mixed-mode resins are needed as orthogonal tools. These technologies can be implemented in flow-through mode allowing for high loadings and fast processing times, making them well-suited for large-scale implementation.

This webinar highlights three case studies that illustrate how novel chromatographic tools can improve the purification process for complex therapeutics by reducing the levels of aggregates and host cell proteins (HCPs) and effectively clearing retroviruses.

Reliable and streamlined workflows to characterize PTMs are necessary to create a comprehensive molecular profile. Workflows that provide these critical pieces of information with minimal processing allow for less labor-intensive characterization of PTMs.