Biotherapeutic drugs are complex and can perform their function through interactions with more than one target molecule. During development and quality control, a range of analytical technologies are used to characterize biotherapeutic drugs in terms of their structural integrity and activity. Ligand-binding assays are relevant for characterization and quantitation of the functional drug, however current analytical approaches may no longer be sufficient for analysis of emerging drug modalities.
Biacore™ assays are based on ligand binding and used in development and characterization of drug product using active concentration measurements, target binding, potency (E50)
and Fc receptor (FcR) analysis.

High concentrations of human lactoferrin (hLF) in human milk offer health benefits for infants and adults, including nourishment and growth support.
Recombinant hLF (rhLF) has been expressed in yeast at an industrial scale, with the aim of making it affordable and accessible as a supplement.
This webinar takes a deep dive into how rhLF can be characterized and analyzed to ensure its safety for consumption in clinical studies.
Our expert speaker will cover how various analytical techniques – including microfluidic modulation spectroscopy – can confirm identity, assess purity and impurities, measure size and investigate the structure of rhLF, as well as compare it to native hLF.

Using data from a recent study, our expert speaker will demonstrate how the new readout platform improves ligand hit quality, and how TIMS offers potential for an expanded scope of AS-MS assays.

The COVID-19 pandemic significantly affected the spread of respiratory pathogens, but their circulation is now returning to pre-pandemic levels.

Attend this webinar to discover how direct analysis in real time (DART), in combination with high-resolution mass spectrometry (HRMS), allows the generation of reliable analytical results much faster and easier than alternative techniques.

In this webinar, you’ll discover how SPR can be multiplexed and automated to enable high-throughput, data-rich drug candidate screening against multiple target proteins.