Psychiatric Disorders Share a Common Genetic BasisNews
Psychiatric disorders such as schizophrenia and bipolar disorder often run in families. In a new international collaboration, researchers explored the genetic connections between these and other disorders of the brain at a scale that far eclipses previous work on the subject. The team determined that psychiatric disorders share many genetic variants, while neurological disorders (such as Parkinson’s or Alzheimer’s) appear more distinct.
Mechanism Controlling Multiple Sclerosis Risk IdentifiedNews
Researchers at Karolinska Institutet have now discovered a new mechanism of a major risk gene for multiple sclerosis (MS) that triggers disease through so-called epigenetic regulation. They also found a protective genetic variant that reduces the risk for MS through the same mechanism.
Synthetic DNA Shuffling Enzyme Outpaces Natural CounterpartNews
A new synthetic enzyme, crafted from DNA rather than protein, flips lipid molecules within the cell membrane, triggering a signal pathway that could be harnessed to induce cell death in cancer cells. Researchers say their lipid-scrambling DNA enzyme is the first in its class to outperform naturally occurring enzymes – and does so by three orders of magnitudeRead more
Antarctic Worm and Machine Learning Help Identify Cerebral Palsy EarlierNews
A research team has released a study in the peer-reviewed journal BMC Bioinformatics showing that DNA methylation patterns in circulating blood cells can be used to help identify spastic cerebral palsy (CP) patients. The technique which makes use of machine learning, data science and even analysis of Antarctic worms, raises hopes for earlier targeted CP therapies.
Genetic Analysis Adds Weight to Cannabis Strain Name ConcernsArticle
Inconsistent naming and labeling of cannabis strains continue to pose challenges for consumers and researchers alike.Read more
We're Not Prepared for the Genetic Revolution That's ComingArticle
New technologies are making genetic information (and the power to manipulate it) more widely available that ever before. What the public do with that information, and the effects of those actions, could be a defining theme of the 21st century.Read more
One Year on, Scientists Defend Canada’s Anti-Genetic Discrimination LawArticle
The Canadian Genetic Non-Discrimination Act (GNA), introduced last May, made it illegal to require individuals to disclose genetic test results or to compel individuals to undergo genetic tests for any agreement or service. However, a subsequent legal challenge has prompted a robust defense of the act from scientists in the May issue of the Canadian Medical Association Journal (CMAJ).Read more
Metagenomics: Exploring Microbiomes at Nature’s New FrontiersArticle
Advances in sequencing technologies are providing scientists with a powerful way to view microbial communities in unprecedented detail. Metagenomics is a rapidly evolving field that is uncovering a wealth of hidden biodiversity, revolutionizing our understanding of uncharted corners in the living world.Read more
Tracking the Heritability of Cell StressArticle
As part of work recently published in Science Advances, a team of researchers from the Institute of Systems Biology at Yale University has built a microfluidic device to demonstrate that single cells preserve a memory of their mother's dynamic response to glucose limitation stress for multiple generations.Read more
The 3D Structure of Telomerase: Uncovering Its Role in Human DiseaseArticle
Researchers have published the first detailed picture and description of the 3-dimensional molecular structure of telomerase – a discovery that could enable better targeted drug screening and could result in more successful telomerase-related clinical therapeutics.Read more