Sequencing the Microbiome: Five Recent Advances
Download this listicle to discover recent research highlights such as the role of the microbiome in food allergies, sequencing microbiome dynamics and overturning conventions in human urology.
Bacillus Strains Could Help To Protect Banana Crops
The Fusarium wilt is a fungus that attacks the banana plant and causes the plant to dry up and die. One of the most dangerous strains is the Tropical Race 4 (TR4) and it seriously threatens banana production globally. Scientists have explored disease-biocontrol agents of five Bacillus strains that display antibiotic ability against TR4.
Chromosome Positioning in Sperm Is Visualized
Researchers have described chromosome positioning during the formation of spermatozoa. The study will allow studying 3D models of chromosomal territoriality and how its alterations can affect fertility.
Molecular Atlas Reveals How Brain Cells Develop
Using a combination of powerful sequencing techniques and mathematical methods, EPFL researchers have traced the genetic programs that direct the development of each cell in the brain. This molecular map could help researchers to understand how the brain develops and provide insights into a range of conditions, including brain tumors and neurodevelopmental disorders.
The Fight To Adapt as an Asexual Invasive Species
Without the benefits of evolutionary genetic variation that accompany meiotic reproduction, how does an asexual invasive species adapt over time to a new environment to survive?
Latent Regenerative Potential of the Inner Ear Explored
Scientists have identified a natural barrier to the regeneration of the inner ear’s sensory cells, which are lost in hearing and balance disorders. Overcoming this barrier may be a first step in returning inner ear cells to a newborn-like state that’s primed for regeneration.
Teach Me in 10 Hub Page
At Technology Networks we understand the importance of time. That's why we've launched Teach Me in 10 a video series that challenges scientists to present and summarize their research area, a scientific concept, or technology in ten minutes or less.
Inhaled Nanobodies: A Potential Treatment for COVID-19
Dr. Yi Shi, assistant professor in the department of cell biology at the University of Pittsburgh and colleagues are exploring the potential of nanobodies as a treatment for COVID-19. The team recently published findings from preclinical studies on the use of a nanobody called Pittsburgh inhalable Nanobody-21 (PiN-21) that targets the receptor-binding domain (RBD) of the SARS-CoV-2 spike (S) protein.
Speaking Algae: Tapping the Ancient Power of Microalgae Using Synthetic Biology
How do humans tap into microalgae’s “life experience” to acquire valuable knowledge? To do so, we must learn to speak their “language” and translate that information into useful applications for society and its industries. Amazingly, recent strides in microalgae biotechnology, synthetic biology, and biomanufacturing are making that possible.
New Developments in Multiplexing Aim To Reduce Immunoassay Variability
Immunoassays are used for a wide variety of proteomic and genomic applications in drug discovery and development. In this article, we discuss the advantages of multiplexing over single-plex methods and highlight key considerations when developing a multiplex assay.
How To Optimize Next-Generation Sequencing Workflows
Download this guide to learn more about techniques such as bulk tissue RNA sequencing, single-nucleus RNA sequencing and whole-genome DNA sequencing.
Both IHC and ICC are powerful tools that provide insights into gene expression, spatial relationships and biomarker identification in a wide variety of applications. These applications include basic research, assessment of normal and disease states within human and animal tissues and assessment of plant pathology.
Download this guide to discover key considerations when performing PCR, including the concentration and purity of starting sample, primer suitability, downstream applications and annealing temperatures.
Characterizing Structural Variants
Structural variants (SVs) are genomic variants encompassing insertions, deletions, duplications, inversions and translocations. SV analysis is of high importance for increasing our understanding of diseases including cancer, neurological disorders and rare genetic diseases. Using long nanopore sequencing reads, SVs can now be characterized with unprecedented resolution.
6 Innovative Applications of Microbes
Microbes have many beneficial properties and for many years, humans, animals and plants have exploited them for their own benefit. We discuss some of the many and varied uses to which microbes are being applied.
Examining the Reproducibility Crisis
Download this listicle to learn about the importance of reproducibility, why problems in reproducibility persist and steps you can take to improve reproducibility.