RNA-seq: Basics, Applications and Protocol

Article

RNA-seq (RNA-sequencing) is a technique that can examine the quantity and sequences of RNA in a sample using next generation sequencing (NGS). Here, we look at why RNA-seq is useful, how the technique works, and a basic protocol which is commonly used today.

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Next Generation Sequencing for the Masses?

Blog

Thermo Fisher Scientific’s Oncomine Dx Target Test, a cancer diagnostics panel, is set to be made available to 160 million people in the US through both Medicare and Medicaid and private insurers. We spoke with Joydeep Goswami, president of Clinical NGS and Oncology for Thermo Fisher Scientific, about the progress of NGS tests in the clinic.

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Gene Therapy Could End Transfusions for Blood Disorder Patients

Gene Therapy Could End Transfusions for Blood Disorder Patients

News

Beta-thalassemia patients need a regular dose of red blood cells transfused into their body. A new gene therapy that edits faulty genes in the patients' cells could end this monthly ritual.

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How Environmental Pollutants and Genetics Work Together in Rheumatoid Arthritis
News

It is well known that individuals with a particular version of human leukocyte antigen have an increased risk for rheumatoid arthritis, but there has been growing interest in the role of environmental pollutants. In a new mouse study, researchers probed the relationship between the two.

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Southeast Asian Nomads Have Evolved to Hunt Fish Underwater
News

The human spleen can release oxygenated blood cells to allow more time underwater without breathing. A new study has identified that the "Sea Nomad" Bajau people of Indonesia have evolved larger spleens that would allow them to remain underwater for longer.

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How City Life Has Changed the Bumblebee Genome
News

Life in the city is a double-edged sword for bumblebees. Subtle differences in their genome show how these important insects have adapted to the food-rich but fragmented city habitat.

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Study Shows Night Owls Have a 10% Higher Risk of Early Death
Study Shows Night Owls Have a 10% Higher Risk of Early Death
Article

Scientists study link between chronotype and death, and find night owls are at greater risk of health complications and earlier death.

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Why is a Molecule Necessary for Penile Erections Important for Brain Cell Communication?
Why is a Molecule Necessary for Penile Erections Important for Brain Cell Communication?
Article

New research sheds light on neuronal communication and adds more detail to the current picture of brain cell communication at the synapse, and the role of the messenger molecule nitric oxide.

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New Tools for Combating Antibiotic Resistance
New Tools for Combating Antibiotic Resistance
Article

Antibiotic resistance is a serious health problem, causing illnesses that were once easily treatable with antibiotics to morph into dangerous infections, leading to serious disability or even death. To help fight this growing threat, diagnostics companies are developing new tools and techniques that are playing a crucial role in quickly identifying infectious organisms and preventing the inappropriate use of antibiotics.

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The Future for PCR Diagnostics
The Future for PCR Diagnostics
Article

The Nobel Prize winning polymerase chain reaction (PCR) technique revolutionized molecular biology on its invention in 1986 and it has done the same for medical diagnostics over the last 15 years. Being able to copy and multiply specific target DNA molecules has opened the door to diagnosing diseases across multiple areas quickly, accurately, and as time progresses at lower cost.

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Is DNA the Future of Digital Data Storage?
Is DNA the Future of Digital Data Storage?
Article

At the intersection of electronics and biology, the field of DNA data storage aims to develop tools that might enable us to store vast amounts of data in an incredibly safe way: on genetic code. We discussed the field with Twist Bioscience's CEO and co-founder, Emily Leproust.

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Are Carbon Nanotubes a New Asbestos?
Are Carbon Nanotubes a New Asbestos?
Article

Used in myriad applications and showered with praise by researchers, carbon nanotubes (CNTs) are hailed as a "wonder material" for materials science. This lofty position may be jeopardized by a new study that shows CNTs can induce the fatal cancer mesothelioma in the same way as asbestos.

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