10 Things We Didn't Know Last Week - 13 July 2018

List

A round-up of the biggest science stories from this week.

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Proteogenomics: The Path to Personalized Medicine?

Article

Proteogenomics - a multiomic discipline which combines gene, protein and RNA data, has potential to give a true systems perspective on the human body. We look at the techniques that enable proteogenomics analysis, and the potential of the field in the clinic to personalize medicine and battle cancer.

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Multiomics and Metaproteomics: Why More Is Better In Proteomic Data Analysis

Article

Developments in next-gen multi-omics have made it possible to generate and process massive amounts of data that cover anything from genomic mutations to metabolomic and microbiological processes. However, handling and analyzing all this data continues to present challenges to even the most experienced bioinformatics experts. In this article we explore some of the solutions and advancements in multi-omics and metaproteomics data analysis approaches.

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The Deadliest Being on Planet Earth – The Bacteriophage

Video

A war has been raging for billions of years, killing trillions every single day, while we don’t even notice. This war involves the single deadliest being on our planet: The Bacteriophage.

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Protein Repairs Gene Damage in Sperm Precursors

Protein Repairs Gene Damage in Sperm Precursors

News

Researchers have uncovered a key function of ATR, a protein in charge of responding to DNA damage during the formation process of sperm precursor cells. They also showed that inhibiting ATR caused issues that block sperm formation.

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Some Like it Hot - Including Tree Shrews!
News

Spicy foods elicit a pungent or hot and painful sensation that repels most mammals. However, the tree shrew, a species closely related to primates, seems to violate this rule of thumb.

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Natural Product Could Lead to New Class of Commercial Herbicide
News

By looking for microorganism's protective shield, specifically the genes that can make it, a team discovered a new and potentially highly effective type of weed killer. This finding could lead to the first new class of commercial herbicides in more than 30 years.

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Finding the Proteins That Unpack DNA
News

A new method allows researchers to systematically identify specialized proteins that unpack DNA inside the nucleus of a cell, making the usually dense DNA more accessible for gene expression and other functions.

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Cell Culture Quality Control: Blissful Ignorance?
Cell Culture Quality Control: Blissful Ignorance?
Article

How can quality control efforts keep up with the rapid advances in cellular model research? Read on for insights into challenges in recognizing and managing issues in cell culture quality control

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Strawberry’s Properties are More than Skin Deep
Strawberry’s Properties are More than Skin Deep
Article

Everyone loves a perfectly ripe strawberry, right? They count towards your five a day and contain important nutrients, vitamins and antioxidants. But what if science could help breeders make them even better?

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Forensic Analysis Reveals Links Between Sources of Illicit Cannabis
Forensic Analysis Reveals Links Between Sources of Illicit Cannabis
Article

Genetic variations have been used to link cannabis samples to geographical areas of origin, providing insight into the plant's history and possible distribution.

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How the Internet of Things is Connecting Up Lab Ecosystems
How the Internet of Things is Connecting Up Lab Ecosystems
Article

If the 20th century was about improving technology, the 21st century has focused on improving access to technology. In this article, we look at how the "Internet of Things" (IoT) movement is changing research, and find that IoT in the lab is at an important crossroads

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Faster Progress for Cancer Research Requires FAIRer Access to Health and Research Data
Faster Progress for Cancer Research Requires FAIRer Access to Health and Research Data
Article

Advances in research mean researchers have access to more data than ever before, but effectively using and sharing this data has become a major challenge in modern research. In this article, Fiona Nielsen, founder of data platform Repositive, explains how data providers can make access to data easier and more secure.

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The Power of Nanopores for Understanding Proteins -Part 1
The Power of Nanopores for Understanding Proteins -Part 1
Article

We spoke to Professor Giovanni Maglia, group leader in chemical biology at the University of Groningen, about the progress he and his team have been making in turning nanopore technology to solving protein questions.

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