Dr. Yi Shi, assistant professor in the department of cell biology at the University of Pittsburgh and colleagues are exploring the potential of nanobodies as a treatment for COVID-19. The team recently published findings from preclinical studies on the use of a nanobody called Pittsburgh inhalable Nanobody-21 (PiN-21) that targets the receptor-binding domain (RBD) of the SARS-CoV-2 spike (S) protein.

On December 31, 2019, the first cases of a novel coronavirus were identified in Wuhan City, Hubei Province, China. Here, we curate a collection of news and content related to what has become the COVID-19 pandemic.

Both IHC and ICC are powerful tools that provide insights into gene expression, spatial relationships and biomarker identification in a wide variety of applications. These applications include basic research, assessment of normal and disease states within human and animal tissues and assessment of plant pathology.

Structural variants (SVs) are genomic variants encompassing insertions, deletions, duplications, inversions and translocations. SV analysis is of high importance for increasing our understanding of diseases including cancer, neurological disorders and rare genetic diseases. Using long nanopore sequencing reads, SVs can now be characterized with unprecedented resolution.