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What's the Physiological Relevance? A Profile of Oded Rechavi

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A profile piece exploring the life and career of the molecular biologist Professor Oded Rechavi.

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Recent Advances and Applications of Single-Cell Sequencing

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Here, we review the most commonly adopted technologies and workflows available for single-cell sequencing and discuss current research studies adopting such approaches.

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Largest Ever DNA Sequencing of Viking Skeletons “Rewrites” History

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Invaders, pirates, warriors – the history books taught us that Vikings were brutal predators who travelled by sea from Scandinavia to pillage and raid their way across Europe and beyond. Now cutting-edge DNA sequencing of more than 400 Viking skeletons from archaeological sites scattered across Europe and Greenland will rewrite the history books.

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Algorithms Uncover Cancers’ Unseen Genetic Losses and Gains
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Scientists have created new mathematical tools that allow scientists to search the vast collection of DNA snippets and uncover whether there are either missing pieces or duplicates. These algorithms, dubbed HATCHet and CHISEL, could help to improve diagnosis and treatment.

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Study of Over 1 Million People Suggests Blood Type O May Protect Against COVID-19
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In June, Technology Networks reported on some of the initial findings from personal genomics and biotechnology company 23andMe's COVID-19 genetic study. These results lent further evidence to earlier suggestions that an individual's blood type – determined by a gene known as ABO – may be associated with COVID-19 susceptibility. Now, 23andMe scientists have published results from the first four months of the study which has collected data from over 1 million research participants.

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Imaging the ORC Complex Responsible for Genome Replication
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Cold Spring Harbor Laboratory (CSHL) Professor & HHMI Investigator Leemor Joshua-Tor and colleagues published images of the human ORC in exquisite detail in eLife, showing how it changes shapes in dramatic ways as it assembles around DNA.

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Advances in Cell Line Development for Neurodegenerative Diseases

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Progression in cell line development has served as the foundation for countless discoveries and advancements in biology and biomedicine – in this article, discover how such developments are being applied in neurodegenerative disease research.

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The Coronavirus Outbreak
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On December 31, 2019, the first cases of a novel coronavirus were identified in Wuhan City, Hubei Province, China. Here, we curate a collection of news and content related to the outbreak.

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Urinary DNA Adductomics: The Next Generation of Omics Technology
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What are DNA adducts? How can we measure them in a non-invasive manner and what can they teach us about human health and disease? This article by Marcus Cooke from the University of South Florida explains all.

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Vital Lessons for the Diagnostics Industry From COVID-19
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While coronavirus has brought together the industry around a common goal, it has also shone a light on the challenges in developing and bringing diagnostic tests to market in exceptional circumstances. It is important that we learn from these challenges so that our industry is better prepared.

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