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Biomarkers and the Future of Precision Medicine

Blog

Biomarkers hold immense potential for the future of medicine, enabling more efficient and better-targeted treatments. Most coverage of novel biomarkers to date has been focused on how a patient’s genetic signature can indicate their susceptibility to a disease, but there is a world of other biological and environmental information that can impact how patients respond to treatments. In this blog, SCIEX’s Aaron Hudson explains how non-genetic biomarkers have a key role to play in reaching the goal of truly precise medicine.

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NGS Workflows: A Simpler Life Through Software

Blog

Having too much data sounds like a nice problem to have. But Next Generation Sequencing (NGS) data’s ubiquity poses challenges as well as opportunities for geneticists. Quick, accurate and reliable workflows are top of the average geneticist’s wishlist. We caught up with OGT’s Dave Cook to discuss the challenges of NGS data, and how software can make things simpler.

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Microbiome Medicine Takes Center Stage

Article

Personalized medicine isn’t all about our DNA. Researchers are increasingly looking past the information encoded on our genes to find answers to how individual variation contributes to complex disease. Companies like the Cambridge-based Microbiotica are much more interested in the bacterial cells that live inside us; our microbiome.

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Day Blind Sheep Cured by Gene Therapy

Day Blind Sheep Cured by Gene Therapy

News

Back in 2009, researchers identified a herd of Awassi sheep suffering from "day blindness". As that term implies, these sheep were blind during the day (in bright light) but could see at night, in low-light conditions. After identifying the genetic basis of this blindness, researchers have now successfully used gene therapy to restore their daytime vision.

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Multiple Malware Threats for Visitors to Pirate Websites
News

Over 4 000 files containing malware or potentially unwanted programmes were retrieved from more than 1 000 websites suspected of sharing illegally protected content in an EU-wide research project carried out by the European Union Intellectual Property Office (EUIPO).

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Marker Indicates Those at Higher Risk from Lethal Fungal Spores
News

Genetic mutation in humans linked to a 17-fold increase in the amount of dangerous fungal spores in the lungs.

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How the Cell Copes With Stress
News

Researchers from the Department of Biochemistry and Molecular Biology at the UAB and from the United Kingdom, for the first time describe the mechanism used by cells to optimise protein production in stressful situations through the altering of tRNA abundance.

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Three Ways to Turn Life Science Suppliers into Partners
Three Ways to Turn Life Science Suppliers into Partners
Article

A growing number of life science businesses are turning to greater supply chain collaboration for benefits like accelerated time to market, improved quality, reduced risk and more rapid and widespread innovation. But while 68% of executives in this industry say active and meaningful engagement with suppliers is essential to success, far too many, over a third, struggle to implement it.

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Lytic vs Lysogenic – Understanding Bacteriophage Life Cycles
Lytic vs Lysogenic – Understanding Bacteriophage Life Cycles
Article

Bacteriophage (phage) are obligate intracellular viruses that specifically infect bacteria. Here we take an overview of their structure, life-cycle and the role they have played in advancing science and medicine.

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Studying the Genome One Cell at a Time
Studying the Genome One Cell at a Time
Article

In 2013, Nature named single-cell sequencing (SCS) as the ‘Method of the Year’, citing its potential to transform the fields of biology and medicine. Now, the technique is bringing to light how genetic information can change between individual cells and facilitating the study of rare cell types. This article explores how these insights have helped scientists understand how diseases like cancer can evolve and spread in humans.

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The Agricultural Perspective on Water Contamination by Pharmaceuticals
The Agricultural Perspective on Water Contamination by Pharmaceuticals
Article

Despite centuries of research into drug development, investigation into the environmental impact of pharmaceuticals is a much younger field. If not treated effectively, there is the potential for pharmaceuticals in wastewater to affect the agricultural industry through the use of this contaminated water supply.

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Genome Editing and Human Reproduction: Behind the Headlines of the Nuffield Council on Bioethics Report
Genome Editing and Human Reproduction: Behind the Headlines of the Nuffield Council on Bioethics Report
Article

Two weeks ago, the Nuffield Council on Bioethics released a seminal report on the social and ethical issues of heritable genome editing. In an article written exclusively for Technology Networks, Hugh Whittall, Director of the Council, looks in-depth at the conclusions and implications of the Council's report.

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GM Crop Ruling Shows Why the EU’s Laws Are Wholly Inadequate
GM Crop Ruling Shows Why the EU’s Laws Are Wholly Inadequate
Article

Ottoline Leyser, Director of the Sainsbury Laboratory, University of Cambridge writes for the Conversation on the flaws behind a new ruling by the European Court of Justice that reclassifies genetic modification as any technique that induces genetic changes “in a way that does not occur naturally”.

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