The Gene Factory: Can Enzymes Revolutionize Man-Made DNA Synthesis?

Article

Building artificial DNA sounds like a technology out of science fiction, but has been conducted in labs for nearly 40 years. To make the potential of synthetic DNA a reality, new methods are being developed that aim to make creating DNA as fast as sequencing it.

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New Software Finds Disease Genes Faster

News

A new study, affiliated with UNIST has recently presented a novel statistical algorithm, capable of identifying potential disease genes in a more accurate and cost-effective way. This algorithm has also been considered as a new promising approach for the identification of candidate disease genes, as it works effectively with less genomic data and takes only a minute or two to get results.

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One Year on, Scientists Defend Canada’s Anti-Genetic Discrimination Law

Article

The Canadian Genetic Non-Discrimination Act (GNA), introduced last May, made it illegal to require individuals to disclose genetic test results or to compel individuals to undergo genetic tests for any agreement or service. However, a subsequent legal challenge has prompted a robust defense of the act from scientists in the May issue of the Canadian Medical Association Journal (CMAJ).

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Gene Editing Technology May Improve Accuracy of Predicting Heart Disease Risk
Gene Editing Technology May Improve Accuracy of Predicting Heart Disease Risk
News

Scientists may now be able to predict whether carrying a specific genetic variant increases a person’s risk for disease using gene editing and stem cell technologies.

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Network Biology Reveals Plant Pathogen Targets
Network Biology Reveals Plant Pathogen Targets
News

How are proteins in the cells of a flowering plant similar to social networks on Twitter or Facebook? And how might both of those be related to the way pathogens make plants or people sick?

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New Subtype of Prostate Cancer
New Subtype of Prostate Cancer
News

Researchers led by the University of Michigan Rogel Cancer Center have identified a new subtype of prostate cancer that occurs in about 7 percent of patients with advanced disease.

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Recruiting Microbes to Combat Cholera Infection
Recruiting Microbes to Combat Cholera Infection
News

MIT engineers have developed a probiotic mix of natural and engineered bacteria to diagnose and treat cholera, an intestinal infection that causes severe dehydration.

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Genetic Discovery Helps Determine the Difference Between Aggressive & Benign Bone Tumors
Genetic Discovery Helps Determine the Difference Between Aggressive & Benign Bone Tumors
News

The first genetic marker for the bone tumor, osteoblastoma, has been discovered. Whole-genome and transcriptome sequencing of human bone tumors revealed that a genetic change that affects the transcription factor, FOS, is a hallmark mutation of osteoblastoma. The results will help clinicians correctly distinguish benign osteoblastoma tumors from aggressive osteosarcoma tumors and direct the correct treatment.

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Improved Method for Isolating Extracellular RNA
Improved Method for Isolating Extracellular RNA
News

In a breakthrough that could lead to powerful new ways to diagnose and track a wide range of medical conditions, scientists at The Rockefeller University have devised an improved method for isolating and identifying tiny fragments of RNA in human blood products.

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We're Not Prepared for the Genetic Revolution That's Coming
We're Not Prepared for the Genetic Revolution That's Coming
Article

New technologies are making genetic information (and the power to manipulate it) more widely available that ever before. What the public do with that information, and the effects of those actions, could be a defining theme of the 21st century.

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Metagenomics: Exploring Microbiomes at Nature’s New Frontiers
Metagenomics: Exploring Microbiomes at Nature’s New Frontiers
Article

Advances in sequencing technologies are providing scientists with a powerful way to view microbial communities in unprecedented detail. Metagenomics is a rapidly evolving field that is uncovering a wealth of hidden biodiversity, revolutionizing our understanding of uncharted corners in the living world.

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Tracking the Heritability of Cell Stress
Tracking the Heritability of Cell Stress
Article

As part of work recently published in Science Advances, a team of researchers from the Institute of Systems Biology at Yale University has built a microfluidic device to demonstrate that single cells preserve a memory of their mother's dynamic response to glucose limitation stress for multiple generations.

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The 3D Structure of Telomerase: Uncovering Its Role in Human Disease
The 3D Structure of Telomerase: Uncovering Its Role in Human Disease
Article

Researchers have published the first detailed picture and description of the 3-dimensional molecular structure of telomerase – a discovery that could enable better targeted drug screening and could result in more successful telomerase-related clinical therapeutics.

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Phenotypic versus Target-based Screening for Drug Discovery
Phenotypic versus Target-based Screening for Drug Discovery
Article

Target-based screening has been the method of choice in drug discovery for the past two decades, but phenotypic screening is having something of a renaissance. We look at the advantages and applications of both.

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Study Shows Night Owls Have a 10% Higher Risk of Early Death
Study Shows Night Owls Have a 10% Higher Risk of Early Death
Article

Scientists study link between chronotype and death, and find night owls are at greater risk of health complications and earlier death.

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