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PromethION in action, in labs around the world

Video

The PromethION is Oxford Nanopore Technologies' largest sequencing device, capable of delivering many terabases of data, in real time, from a single run. Hear how teams across a broad range of applications, based in labs all over the world — US (UCSF, UCD, JCVI and UCSC), China (GrandOmics and Biomarker) and Europe (KeyGene, Genescope and UMC Utrecht) — are using PromethION in their work.

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10 Things We Didn't Know Last Week - 12 October 2018

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A weekly round-up of the latest news stories.

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10 Things We Didn't Know Last Week, October 5, 2018

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A roundup of the top life science news nuggets from the week, guaranteed to make you sound more interesting

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New Approach for Controlling Dengue Fever and Zika virus
New Approach for Controlling Dengue Fever and Zika virus
News

Gene-editing tool to disrupt serotonin receptor linked to egg production in Aedes aegypti mosquitoes.

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Tracking Down Missing-in-Action Multiple Sclerosis Genes
Tracking Down Missing-in-Action Multiple Sclerosis Genes
News

Previous work by the International Multiple Sclerosis Genetics Consortium (IMSGC) has identified 233 genetic risk variants. However, these only account for about 20% of overall disease risk, with the remaining genetic culprits proving elusive. A new study has tracked down four of these hard-to-find genes.

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New File Type Aims to Secure Genomic Data
New File Type Aims to Secure Genomic Data
News

Based on an analysis of data leakages and opportunities to prevent the potential misuse of genetic information, researchers have developed a new file format for functional genomics data that enables data sharing while protecting the personal information of research participants.

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Marker May Help Target Treatments for Crohn’s Patients
Marker May Help Target Treatments for Crohn’s Patients
News

Accurately predicting which subtype of Crohn's disease is likely to develop has not been possible, until now.

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Breast­feed­ing Protects Babies from An­ti­bi­otic-res­ist­ant Bac­teria
Breast­feed­ing Protects Babies from An­ti­bi­otic-res­ist­ant Bac­teria
News

Babies that are breastfed for at least six months have less antibiotic-resistant bacteria in their gut compared with infants breastfed for a shorter time.

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Attacking RNA with Small-molecule Drugs
Attacking RNA with Small-molecule Drugs
News

Yale researchers have developed a way to target RNA with small-molecule drugs, creating a new method for tapping into a vast number of biological mechanisms critical to metabolism and gene expression.

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Exploiting Epigenetics in Cancer Treatment
Exploiting Epigenetics in Cancer Treatment
Article

Changes to the complex of DNA and the proteins that form chromatin are important drivers in many cancers. We explore the challenges and progress in the development of new therapies targeting epigenetic regulators.

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Exploring the Public’s Perception of Food Fraud
Exploring the Public’s Perception of Food Fraud
Article

When you go to the shops to buy the weekly groceries, it’s quite likely you’ll find yourself thinking about where your food has come from. Is this organic? Is that free-range? You are perhaps less likely to find yourself wondering, “Is this food fake?”

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Understanding the Lytic Cycle – What Are the Steps?
Understanding the Lytic Cycle – What Are the Steps?
Article

Bacteriophage (phage) are viruses that specifically infect bacteria. They have a two-phase lifecycle, residing in a dormant state within the host genome (lysogenic cycle) or hijacking the host cellular machinery for their own replication (lytic cycle). Here we will explore the important steps of the lytic cycle.

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Cold Plasma for Seed, Fruit and Vegetable Decontamination and Plant Disease Control
Cold Plasma for Seed, Fruit and Vegetable Decontamination and Plant Disease Control
Article

An effective way to increase crop yield is to minimize losses to pathogenic microorganisms by improving the disease resistance of crop plants. A recently emerging alternative to conventional methods for improving plant disease resistance is cold plasma.

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The Genetics of Coffee Consumption
The Genetics of Coffee Consumption
Article

Marilyn Cornelis, of the Feinberg School of Medicine at Northwestern University, has spent years researching how coffee affects our body. In this interview, she explains how coffee affects our brain, interacts with cannabis, and why listening to your body might be the best way to decide how much coffee to drink.

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MALDI Imaging Mass Spectrometry (MALDI IMS): A Marriage of Mass Spectrometry and Morphological Spatial Resolution
MALDI Imaging Mass Spectrometry (MALDI IMS): A Marriage of Mass Spectrometry and Morphological Spatial Resolution
Article

Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) is a powerful analytical technique that enjoys the sensitivity of mass spectrometry coupled with spatial distribution information.

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