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Antimicrobial Resistance: Drivers, Diagnostics and DNA

List

Combating AMR is going to take coordinated action of different approaches, such as improved public education and national action plans, greater surveillance, improved diagnostics, and the ability to harness advances in genomics and big data.

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Code of the Wild Film Trailer

Video

Code of the Wild explores the public and secret worlds of genetic engineering. Award-winning producer/director Cody Sheehy and CRISPR scientist Samira Kiani filmed for 18 months in United States and China documenting the biohackers and scientists involved in editing humans. Their team brought world attention to the secret work of Dr. Jiankui He, who first enhanced human babies in an attempt to make them immune to HIV. This story is at the heart of a revolution that will transform how we live and how we die.

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Finding the Key to Flightlessness
News

Since Darwin's era, scientists have wondered how flightless birds like emus, ostriches, kiwi, cassowaries and others are related, and for decades the assumption was that they must all share a common ancestor who abandoned the skies for a more grounded life. A team of Harvard researchers believes they may now have part of the answer.

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Using CRISPR to Build Computers Inside Human Cells
News

Researchers have integrated two CRISPR-Cas9-based core processors into human cells. This represents a huge step towards creating powerful biocomputers.

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CRISPR Treats Lethal Lung Disease Before Birth in Animal Model
News

Using CRISPR gene editing, a team from Children's Hospital of Philadelphia (CHOP) and Penn Medicine have thwarted a lethal lung disease in an animal model in which a harmful mutation causes death within hours after birth.

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Gene Therapy Restores Immunity in Infants With Rare Immunodeficiency Disease
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A small clinical trial has shown that gene therapy can safely correct the immune systems of infants newly diagnosed with a rare, life-threatening inherited disorder in which infection-fighting immune cells do not develop or function normally.

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The Leukemia Atlas: A Guide to Proteins That Signal Disease
News

Only about one in four people diagnosed with acute myelogenous leukemia (AML) survive five years after the initial diagnosis. To improve that survival rate, researchers have created an online atlas to identify and classify protein signatures present at AML diagnosis.

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An Epigenetic Approach to Tackling World Hunger?
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Researchers have discovered a new way to regenerate flowering plant tissues, opening possibilities of mitigating global food problem.

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The Evolving Field of Cancer Biomarkers
Article

Given the complexity of cancer, it’s arguably unlikely that single molecules will work as clinically meaningful biomarkers for cancer. Today, biomarker discovery involves detecting patterns – characteristics or phenotypes that can be measured and monitored throughout a patient’s journey. Here, we look at two approaches being explored in this evolving field.

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Sensitivity vs Specificity
Article

When developing diagnostic tests or evaluating results, it is important to understand how reliable those tests and therefore the results you are obtaining are. By using samples of known disease status, values such as sensitivity and specificity can be calculated that allow you to evaluate just that.

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Personalized Nutrition Makes Dietary Advice Easier to Chew
Article

In an age where advanced high-throughput-omic technologies allow for cheaper and faster screening of the genome, consumer genomics is becoming increasingly mainstream and a growing number of people are opting to purchase genetic tests for a variety of purposes, including personalized nutrition advice.

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NASA Identical Twin Study Takes Our Understanding of Space Travel to the Final Frontier
Article

Identical male twins Scott and Mark Kelly - both (now retired) NASA astronauts – spent one year apart as Scott travelled to and inhabited the International Space Station (ISS), whilst Mark stayed at home on earth. Researchers have gained valuable insights from the study results as to the physiological effects of space travel.

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Genome Editing Database Helps Researchers Pull Together to Advance Agriculture
Article

The Boyce Thompson Institute's Plant Genome Editing Database has been created by scientists to encourage sharing of data from experiments where CRISPR/Cas9 technology, along with other approaches to gene editing, have been used to study economically important traits in plants. We spoke to Zhangjun Fei and David Stern from the institute to learn more.

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The Power of Proteogenomics in Precision Medicine
Article

Part of the "systems biology" trend, proteogenomics is expanding at an accelerating rate. In this article, we look at the approaches adopted in proteogenomics and explore how proteogenomics is changing the dynamics of precision medicine in oncology.

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