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Novel Discovery of "Hidden" Gene Within a Gene in Mammals

Article

Scientists have discovered a novel overlapping coding sequence in the gene POLG . What does this mean? Is there a "hidden" genome? Technology Networks spoke with researcher Yousuf Khan to find out more.

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Ancient Fossil Reveals Origin of Human Hand

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3D animation of an ancient Elpistostege fish fossil found in Miguasha, Canada has revealed new insights into how the human hand evolved from fish fins.

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Using Single Cells To Get the Whole Picture of the Epigenome

Article

In this article, we explore the advancements of single-cell sequencing methods such as scATAC-seq, and how these methods allow the mapping of large cell populations, one cell at a time. How does this information enhance our understanding of the epigenome?

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Progress Made Towards a Simple, Low-cost CRISPR-based SARS-CoV-2 Diagnostic
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Researchers at the University of Connecticut have been working to develop a new, low-cost, CRISPR-based diagnostic platform to detect infectious diseases, including the novel coronavirus (SARS-CoV-2).

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The First Genetic Map of the Cerebral Cortex
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Researchers have produced the first genetic map of the cerebral cortex, identifying more than 300 genetic variants that influence cortical structure and could play roles in psychiatric conditions.

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Tears Low Risk for Coronavirus Spread
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While researchers are certain that coronavirus spreads through mucus and droplets expelled by coughing or sneezing, new data shows it is unlikely to spread via tears.

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Jumping Genes Help Make Neurons in a Lab Dish
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The process of making functional brain cells in a lab dish requires the precise activation of selfish genetic elements known as LINE-1 (L1) retrotransposons. The finding, from researchers at KAUST, could lead to safer and more effective regenerative therapies for Parkinson's disease and other brain conditions.

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The Genetic Quest To Understand COVID-19
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How the novel coronavirus that causes COVID-19 made the leap from animals to humans is a puzzle that scientists are trying to solve as humanity comes to grip with the deadly pandemic sweeping the globe.

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Study Provides Insights Into the Diagnosis and Treatment of Pediatric Brain Cancer
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In a recent study published in Autophagy, researchers at Kanazawa University show how abnormalities in a gene called TPR can lead to pediatric brain cancer.

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Cell Signaling Insights Leveraged for Glaucoma and Cancer Therapy Development

Article

In this article, we delve into some of the cell signaling pathways involved in glaucoma and cancer and how they represent promising new approaches to treatment.

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The Future of Pharma Beyond Blockbusters
Article

Each individual’s genetic makeup is slightly different from everyone else’s, so why are we all receiving the same medicine? To put it simply – the lucrative blockbuster business model, which has previously been the key to pharma success, is no longer viable. In a global and fast-moving world, in order to evolve, it’s time to examine new alternatives to the classic structure.

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ADME Advances: Personalized and Computational Approaches
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ADME profoundly affects a drug’s properties and has long been a cornerstone of pharmacology and drug discovery. Recent years, however, have seen an evolution in ADME concepts. Here, we take a closer look at the impact personalized and computational approaches are having on a drug's pharmacology.

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Gene vs Allele: Definition, Difference and Comparison
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Genes and alleles are essential to basic genetics, but what are the differences between them? In this guide, we compare genes and alleles and provide simple definitions and examples for both.

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