CRISPR-Cas9 ("Mr. Sandman" Parody)

Fun Video

A Capella Science parodies "Mr Sandman" with his latest video (and hopefully teaches you something about CRISPR-Cas9 gene editing).

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10 Things We Didn't Know Last Week - June 22, 2018

List

A roundup of the weeks biggest stories in science

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The Gene Factory: Can Enzymes Revolutionize Man-Made DNA Synthesis?

Article

Building artificial DNA sounds like a technology out of science fiction, but has been conducted in labs for nearly 40 years. To make the potential of synthetic DNA a reality, new methods are being developed that aim to make creating DNA as fast as sequencing it.

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Antiviral Gene Vanquishes Zika

Antiviral Gene Vanquishes Zika

News

It’s been known for years that humans and other mammals possess an antiviral gene called RSAD2 that prevents a remarkable range of viruses from multiplying. Now, researchers at Albert Einstein College of Medicine, part of Montefiore, have discovered the secret to the gene’s success: The enzyme it codes for generates a compound that stops viruses from replicating. The newly discovered compound, described in today’s online edition of Nature, offers a novel approach for attacking many disease-causing viruses.

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Discovery Advances Efforts to Prevent Spread of Cancer
News

Newly identified gene targets could be key to preventing the spread of cancer, new University of Alberta research has shown.

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Streaming Protocol Makes Gene Data Sharing Future-Proof
News

The Large Scale Genomics Work Stream of the Global Alliance for Genomics and Health (GA4GH) has announced eight new implementations of its htsget protocol, a standard released in October 2017 for accessing large-scale genomic sequencing data online that does not depend on file transfers. The protocol and interoperability testing are reported in a paper released online this week in the journal Bioinformatics.

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Mechanism Controlling Multiple Sclerosis Risk Identified
News

Researchers at Karolinska Institutet have now discovered a new mechanism of a major risk gene for multiple sclerosis (MS) that triggers disease through so-called epigenetic regulation. They also found a protective genetic variant that reduces the risk for MS through the same mechanism.

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Genetic Analysis Adds Weight to Cannabis Strain Name Concerns
Genetic Analysis Adds Weight to Cannabis Strain Name Concerns
Article

Inconsistent naming and labeling of cannabis strains continue to pose challenges for consumers and researchers alike.

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We're Not Prepared for the Genetic Revolution That's Coming
We're Not Prepared for the Genetic Revolution That's Coming
Article

New technologies are making genetic information (and the power to manipulate it) more widely available that ever before. What the public do with that information, and the effects of those actions, could be a defining theme of the 21st century.

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One Year on, Scientists Defend Canada’s Anti-Genetic Discrimination Law
One Year on, Scientists Defend Canada’s Anti-Genetic Discrimination Law
Article

The Canadian Genetic Non-Discrimination Act (GNA), introduced last May, made it illegal to require individuals to disclose genetic test results or to compel individuals to undergo genetic tests for any agreement or service. However, a subsequent legal challenge has prompted a robust defense of the act from scientists in the May issue of the Canadian Medical Association Journal (CMAJ).

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Metagenomics: Exploring Microbiomes at Nature’s New Frontiers
Metagenomics: Exploring Microbiomes at Nature’s New Frontiers
Article

Advances in sequencing technologies are providing scientists with a powerful way to view microbial communities in unprecedented detail. Metagenomics is a rapidly evolving field that is uncovering a wealth of hidden biodiversity, revolutionizing our understanding of uncharted corners in the living world.

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Tracking the Heritability of Cell Stress
Tracking the Heritability of Cell Stress
Article

As part of work recently published in Science Advances, a team of researchers from the Institute of Systems Biology at Yale University has built a microfluidic device to demonstrate that single cells preserve a memory of their mother's dynamic response to glucose limitation stress for multiple generations.

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The 3D Structure of Telomerase: Uncovering Its Role in Human Disease
The 3D Structure of Telomerase: Uncovering Its Role in Human Disease
Article

Researchers have published the first detailed picture and description of the 3-dimensional molecular structure of telomerase – a discovery that could enable better targeted drug screening and could result in more successful telomerase-related clinical therapeutics.

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