Deep Learning Helps Tease Out Gene Interactions
NewsConvolutional neural networks could be used to help identify disease-related genes and genetic pathways that could be targets for drugs.
Read moreHow To Hide Data in Everyday Objects
NewsResearchers have developed a means of storing extensive information in almost any object. The way of storing this information is the same as for living things: in DNA molecules.
Read moreGut Feeling: A Network-based Approach Towards Understanding IBD
NewsScientists have discovered how to get detailed transcriptomics data from gut organoids, and regulatory networks to analyze them, establishing a pipeline that can be used to explore the causes of inflammatory bowel disease.
Read moreIncreasing Food Intake by Swapping Mitochondrial Genomes
NewsTo uncover the relationship between variation in genes and phenotypic diversity, geneticists use a set of fully sequenced fruit-fly genomes. But little is known about the variation in the mitochondrial genome, for which mutations are linked to an array of diseases. Now, EPFL scientists have created a high-resolution map of mitochondrial DNA variants in the fruit fly, connecting mitochondrial genes to metabolic traits and diseases.
Read moreBacteria Detox Using RNAs
NewsUsing a new technique, NAIL-MS, researchers have discovered a novel type of chemical modification in bacterial RNAs. The modification is apparently attached to molecules only when cells are under stress, and is rapidly removed during recovery.
Read moreThe Role of Genetics in Sight and Preventing Blinding Eye Diseases
NewsResearchers have discovered unique patterns of genetic activity that could lead to development of blinding retinal diseases.
Read moreScream If You Wanna Go FASTA: Breaking the Bottleneck in Genomic Data Analysis
ArticleIn the post-genomic era, the direct cost associated with performing sequencing reactions has diminished, whereas the data processing, storage, management, and interpretation costs have increased exponentially. In this article, we explore how new tools are simplifying the process of genomic data analysis.
Read moreScientists Left Perplexed at Latest Alzheimer’s Drug Data
ArticleIn this article, we revisit the many twists and turns of the aducanumab clinical trials and explore the scientific community's response to the latest analysis of the data.
Read moreAdvances in PCR Diagnostics for Cancer and Medical Mycology
ArticleFrom detecting cancer to microbial infections, and now even fungal infections, PCR has become the gold standard of analyzing gene expression. In this article, we explore how PCR is used as a novel diagnostic strategy to identify clinically important yeast species, as well as to detect mutations that could guide therapeutic decisions for lung cancer patients.
Read moreKey Themes and Conversations From the First Lab of the Future Congress
ArticleWhat do we mean by lab of the future? What innovations are required to get there? These are the key themes explored by this year's Lab of the Future Congress, summarized in this article.
Read moreTechnology Networks Explores the CRISPR Revolution: An Interview With Professor Glenn Cohen, World-leading Expert on Bioethics
ArticleIn this feature of Technology Networks Explores the CRISPR Revolution, we interview Professor Glenn Cohen, director of Harvard Law School's Petrie-Flom Center for Health Law Policy, Biotechnology and Bioethics.
Read moreMetabolomics: A “Go-to” Approach in Systems Biology
ArticleThe measurement of low-molecular-weight metabolites and their intermediates reflects the dynamic response of the body to physiological, pathophysiological and developmental stimulus (e.g., aging). In this article, we explore how metabolomic profiling is advancing an array of scientific disciplines, including medicine and agriculture.