Metagenomics: Exploring Microbiomes at Nature’s New Frontiers

Article

Advances in sequencing technologies are providing scientists with a powerful way to view microbial communities in unprecedented detail. Metagenomics is a rapidly evolving field that is uncovering a wealth of hidden biodiversity, revolutionizing our understanding of uncharted corners in the living world.

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10 Things We Didn't Know Last Week - 18 May 2018

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The most exciting science new stories from the last 7 days

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10 Things We Didn't Know Last Week - 11 May 2018

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The most exciting science from the last 7 days

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Yeast Study Performs Hundreds of Simultaneous CRISPR Edits

Yeast Study Performs Hundreds of Simultaneous CRISPR Edits

News

A new technique which can alter hundreds of different genes at once in baker's yeast could greatly speed up CRISPR-Cas9 editing and offer a way to perform high-throughput functional genomics.

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New Inherited Neurodevelopmental Disease Discovered
News

Researchers have identified a new inherited neurodevelopmental disease that causes slow growth, seizures and learning difficulties in humans.

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Bird and Turtle Chromosomes Help Identify Dinosaur DNA
News

Researchers have used bird and turtle DNA to extrapolate the chromosome structure of their common ancestor that lived around 260 million years ago – 20 million years before the dinosaurs first emerged. They were then able to trace the evolution of avian and non-avian dinosaur DNA through to the present day.

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Over 130 Glaucoma Gene Variants Could Help Predict Blindness
News

An international study has identified 133 genetic variants that could help predict the risk of developing glaucoma, the world’s leading cause of incurable blindness. The findings are an advance in the fight to tackle the incurable, degenerative condition, which has virtually no symptoms in the early stages, and could lead to a genetic-based screening program.

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Tracking the Heritability of Cell Stress
Tracking the Heritability of Cell Stress
Article

As part of work recently published in Science Advances, a team of researchers from the Institute of Systems Biology at Yale University has built a microfluidic device to demonstrate that single cells preserve a memory of their mother's dynamic response to glucose limitation stress for multiple generations.

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The 3D Structure of Telomerase: Uncovering Its Role in Human Disease
The 3D Structure of Telomerase: Uncovering Its Role in Human Disease
Article

Researchers have published the first detailed picture and description of the 3-dimensional molecular structure of telomerase – a discovery that could enable better targeted drug screening and could result in more successful telomerase-related clinical therapeutics.

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Phenotypic versus Target-based Screening for Drug Discovery
Phenotypic versus Target-based Screening for Drug Discovery
Article

Target-based screening has been the method of choice in drug discovery for the past two decades, but phenotypic screening is having something of a renaissance. We look at the advantages and applications of both.

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Study Shows Night Owls Have a 10% Higher Risk of Early Death
Study Shows Night Owls Have a 10% Higher Risk of Early Death
Article

Scientists study link between chronotype and death, and find night owls are at greater risk of health complications and earlier death.

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Why is a Molecule Necessary for Penile Erections Important for Brain Cell Communication?
Why is a Molecule Necessary for Penile Erections Important for Brain Cell Communication?
Article

New research sheds light on neuronal communication and adds more detail to the current picture of brain cell communication at the synapse, and the role of the messenger molecule nitric oxide.

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CRISPR Technology Could Revolutionize Animal Transgenics
CRISPR Technology Could Revolutionize Animal Transgenics
Article

Despite its role in advancing genetics research, transgenic modification of animal models is an aging and costly technique. A new tool that leverages CRISPR technology may make the entire process simpler and more efficient.

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