Efficient Silencing of mRNA and lncRNA with Fewer Off-target Effects

Featured Product

Exiqon LNA™ GapmeRs are powerful tools for loss of function studies of proteins, mRNA and lncRNAs.

Read more

RNA sequencing with nanopore technology

Video

New: nanopore for RNA sequencing. Sequence complete RNA strands directly and in real-time. Or, cDNA ‘strand-switching’ protocol also allows full-length sequencing of cDNA, either with or without PCR amplification.

Watch Now

8 Stories of Lab Safety Gone Wrong

List

Read about eight incidents from which we can all learn important lessons about lab safety.

Read more

Plant Epigenetics: An untapped molecular resource for crop improvement

Article

Epigenetic phenomena such as paramutation, transgenic silencing, imprinting, and transposable element inactivation are prevalent in plants and potentially offer a huge resource for directed crop improvement.

Read more
Genes Can Influence the Mutation, Activity of Nearby Genes
Genes Can Influence the Mutation, Activity of Nearby Genes
News

Study shows that a gene’s neighborhood can influence whether and how the activity of a gene changes.

Read more

Shedding Light on How Tumors Become Resistant to Immunotherapy
Shedding Light on How Tumors Become Resistant to Immunotherapy
News

Researchers have now found that in skin cutaneous melanoma an epigenetic control protein is key to the development of immunotherapy resistance.

Read more

Brain Regions Implicated in Mental Disorders Influenced by Neanderthal Genes
Brain Regions Implicated in Mental Disorders Influenced by Neanderthal Genes
News

Findings indicate that the more a person’s genome carries genetic vestiges of Neanderthals, the more certain parts of his or her brain and skull resemble those of humans’ evolutionary cousins that went extinct 40,000 years ago.

Read more

CRISPR Reveals New Targets for Promising  Cancer Drugs
CRISPR Reveals New Targets for Promising Cancer Drugs
News

Novel screening method identifies new drug targets that could potentially enhance the effectiveness of PD-1 checkpoint inhibitors, a promising new class of cancer immunotherapy.

Read more

DARPA Pours $65 Million Into Making CRISPR Safer
DARPA Pours $65 Million Into Making CRISPR Safer
News

With one eye on potential bioterrorism threats, the Defense Advanced Research Projects Agency has announced $65 million in funding to seven projects around the USA.

Read more

Potential Barcode Identified for a Form of Alcoholic Liver Disease
Potential Barcode Identified for a Form of Alcoholic Liver Disease
News

NIAAA-supported researchers have discovered that extracellular vesicles released by liver cells in a mouse model of alcoholic steatohepatitis contain a miRNA signature detectable in the blood.

Read more