In a study published today in PLOS Biology, researchers from the Wellcome Sanger Institute and the University of Montpellier have reconstructed a ~50,000-year-old gene sequence acquired by the ancestor of Plasmodium falciparum. The acquisition of the gene sequence enabled the parasite to infect human red blood cells.

Genetic differences in the immune system shape the collections of bacteria that colonize the digestive system, according to new research by scientists at the University of Chicago.

Researchers have developed new genetic-based epilepsy risk scores which may lay the foundation for more personalized diagnosis and treatment.

Researchers have uncovered the 56-million-year evolutionary history of oaks.

A team of microbiologists and genomicists led by the Department of Energy Joint Genome Institute (JGI) has invented a genetic engineering tool, called CRAGE, that could not only make studying microbes much easier, but also fill significant gaps in our understanding of how microbes interact with their surroundings and evolve.

Researchers have developed a new system that helps the immune system spot and eliminate cancer cells.

Kicking off Technology Networks Explores the CRISPR Revolution, Professor Mojica, or "Francis", takes us on a journey back to the original research that, despite being deemed "crazy" by members of the scientific community at the time, led to the CRISPR revolution that is anticipated to edit evolution forever.

Reproducibility is now recognized as a core feature of good scientific practice but too many papers fail to meet the grade. We talked to Leslie D McIntosh, CEO of Ripeta, on the topic of reproducibility. In this interview, we ask Leslie about the concepts within Ripeta’s recent report on the state of reproducible science in 2019.

Thus far, the feasibility to edit stem cells using CRISPR technology has been demonstrated in two key areas: modeling and investigating human cell states and human diseases, and regenerative medicine. In this article, we explore some of the latest research in these spaces and the approaches that scientists are adopting to overcome challenges in the field.