The MAPK Pathway as a Therapeutic Target in Cancer Research

Article

Following the rapid and striking success of vemurafenib, a MAPK targeting drug used to treat melanoma, interest in this critical cell signalling pathway has exploded.

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From the lab to the boardroom: An interview with Darlene Solomon Ph.D.

Life In Science

We spoke to Darlene to learn about her reasons for studying science, how she transitioned away from the lab and some of her proudest achievements at Agilent.

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A Year in Genomics Research 2017

Quiz

Genetics has come a long way in it's relatively short life. But, how much do you know about the amazing progress that's been made in 2017? Take this quiz to find out!

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First Successful Gene Therapy Trial Reported for People with Hemophilia A
First Successful Gene Therapy Trial Reported for People with Hemophilia A
News

Patients with hemophilia A who received a single infusion of an investigational gene therapy showed improved levels of the essential blood clotting protein FVIII, with 11 of 13 achieving normal or near-normal FVIII levels.

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Some Immune Cells May Help Tumors Instead of Destroying Them
Some Immune Cells May Help Tumors Instead of Destroying Them
News

New data shows that neutrophils promote tumor progression and can actually hamper the work of immunotherapy in lung cancer.

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Cancer Gene Plays Key Role in Cystic Fibrosis Lung Infections
Cancer Gene Plays Key Role in Cystic Fibrosis Lung Infections
News

Recent findings explain why people with cystic fibrosis are particularly prone to respiratory infections—and suggest a new approach to treatment.

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Oligonucleotide Drug Producers Report on Drug Impurities
Oligonucleotide Drug Producers Report on Drug Impurities
News

A new addition to a series of articles that focus on important topics related to the development of oligonucleotide therapeutics presents an in-depth look at the identification, characterization, and reporting of product-related impurities.

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Exploring African Genetic Diversity Unlocks Disease Susceptibility Traits
Exploring African Genetic Diversity Unlocks Disease Susceptibility Traits
News

African populations harbour the greatest genetic diversity and have the highest per capita health burden, yet they are rarely included in large genome studies of disease association, the authors of this study want to change this fact.

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Searching for the CRISPR Swiss-army Knife
Searching for the CRISPR Swiss-army Knife
News

High-resolution structural comparison of Cpf1 and Cas9 could help researchers achieve more accurate gene editing with CRISPR.

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