Latest Application Notes
Lab Ultrafiltration - Tips and Tricks
Download this compendium to discover tips and tricks for ultrafiltration including how to desalt samples, concentrate samples and recover low-concentrated samples.
Accurate SARS-CoV-2 Surveillance With Resilience to Genomic Variation
Download this app note to discover a surveillance assay that rill remain effective as new variants emerge whilst offering high sensitivity and capture efficiency.
Optimizing Process Efficiency and Sample Extraction
Download this app note to discover a method that includes a new cooling feature which is an efficient way to maintain nucleic acid integrity post-extraction that does not vary in its ability to elute the sample extracts into tubes for biobanking purposes.
Spatially Resolved Heterogeneity of Triple Negative Breast Cancer
Triple negative breast cancer (TNBC) is unresponsive to traditional hormone or targeted therapies and highly heterogeneous. Improved understanding of the biological underpinnings and cell-type composition of TNBC is critical to developing novel targeted treatment options.
Using siRNA Reagents that Achieve Long-Term Gene Silencing
Developing a thorough understanding of a gene’s contribution to a particular phenotype is problematic when the protein has an extended half-life or the phenotype under study requires days to materialize. Under these circumstances, reagents that induce long-term gene silencing are needed to sufficiently deplete internal cellular stores for extended periods of time.
Studying the Molecular Mechanism of Viral Replication in Real Time
Download this app note to discover a fluorescent-based approach that can enable real-time measurement of viral gene expression and be used to study virtually any virus in a 96- or 384- well format.
Tiling Across Viral Genomes to Investigate Immune Escape
Viruses exploit high-dimensional RNA structures to facilitate viral replication and impede host restriction. Here, a novel next-generation sequencing (NGS)-based screening workflow, called Fate-seq, was used to define and characterize high-dimensional RNA structures.
Benefits of an Ergonomic and Electronic Pipette for RT-PCR
Pipetting ergonomics has emerged as an important consideration in the research laboratory, especially during the past year when diagnostic laboratories were forced to work for long hours due to the global SARS-CoV-2 pandemic.
Identifying an Intronic Positive Variant
It can take approximately seven years to diagnose a patient with a rare disease. With NEW CentoXome®, this doesn’t have to be the case.
Rapid Quantitative Analysis of Fermentation Broth Samples
Download this app note to discover a system that achieves high throughput for screening and requires minimal sample preparation.