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Latest App Notes & Case Studies

 Digitally generated DNA fragment on a dark background
App Note / Case Study

Optimize Sequencing Results By Analyzing Moles

This application note introduces a novel approach that enhances the assessment of length distribution and improves the prediction of sequencing outcomes.
A snippet of a DNA helix being captured
App Note / Case Study

Enhancing Precision in RNA-Seq with Target Enrichment

This application note describes a novel design strategy aimed at reducing bias and facilitating the discovery of novel fusion genes.
A scan image of a cancer infected set of lungs
App Note / Case Study

Future-Proof Your RNA-Seq Workflow

This application note describes the use of targeted custom RNA panels to overcome these challenges by enabling the robust and sensitive detection of gene expression profiles from FFPE non-small cell lung cancer samples.
App Note / Case Study

Optimizing RNA Sequencing of FFPE Samples

This application note evaluates several commercially available rRNA depletion kits, providing an optimized protocol for the efficient removal of rRNA from FFPE samples.
gene regulation
App Note / Case Study

Targeted Enrichment for Methylation Analysis

This application note reviews a simple and effective workflow used to study differences in methylation status in mice brain and blood cells.
molecular laboratory
App Note / Case Study

Streamlined NGS Analysis for CNV Identification

This application note explores the use of an intuitive and streamlined solution for NGS analysis, enabling the detection of a broad range of CNVs.
Quality Control
App Note / Case Study

Prepare for NGS Success With Sample Quality Control

This application note showcases an assay that determines sample quality by assessing the degree of fragmentation of input genomic DNA to identify samples that are not fit for purpose prior to NGS.
mRNA Strand
App Note / Case Study

High-Resolution mRNA Poly(A) Tail Analysis With CGE-UV

This application note describes how capillary gel electrophoresis with UV detection (CGE-UV) can attain single-nucleotide resolution over a broad size range, making it suitable for the development of QC assays.
Immune Cell Types
App Note / Case Study

Quantitative Cell Profiling of Immune Cell Types From Whole Blood Samples

This application note explores an optimized RNA-sequencing workflow that reliably determines cell subset abundance and cell-type-specific gene expression profiles from bulk tissue or blood expression data.
Testube for solid Tissue Samples
App Note / Case Study

Quantitative Profiling of Cell Type Composition in Solid Tissue Samples

This application note explores the performance characteristics of a tissue panel for profiling both FF and FFPE tissue samples using a state-of-the-art software solution for digital cytometry.