Latest App Notes & Case Studies

In this experiment, a crude insect preparation and a DNAble assay were used to demonstrate that the AmpliFire instrument accurately detects the presence of HLB-causing bacteria consistent with a real-time PCR system. The AmpliFire offers greater portability than real-time PCR instrumentation, and is a powerful tool for point of use applications such as management of citrus greening disease.

The IntelliQube® from Douglas Scientific® is designed to address the need for accurate and reliable results for studies such as CNV determination.

The IntelliQube performs at an industry leading level, facilitating outstanding qPCR results with Array Tape® and the added benefits of inline automation. Liquid handling, thermal cycling, and detection systems within the IntelliQube enables users to achieve efficient and economical high throughput sample processing in Array Tape without compromising important parameters of qPCR performance.

Changes in microRNA (miRNA) expression have been shown to be associated with a variety of normal physiological processes, as well as diseases including cancer. Studies have already shown that miRNAs may provide useful markers for the development of disease diagnostic and prognostic assays.

This study demonstrates that the Nexar® with the FlexJet multi-array dispense feature can reduce master mix consumed as dead volume by 87.5% compared to Dispense Jet single-array dispense. The capability to perform multi-array dispense with one aspiration also produces repeatable and accurate results and is an ideal solution for genotyping applications.

This study demonstrates the ability of the IntelliQube along with Array Tape®, to successfully achieve two multiplexed SNP genotyping results in a single well and decrease thermal cycling times without compromising data quality. The combination of achieving two results per reaction well and shortened cycling times dramatically increases overall throughput.

This study evaluated multiplex genotyping on the IntelliQube, a PCR instrument optimized for 1.6 µL reaction volumes in Array Tape®. It demonstrates the feasibility of achieving two SNP genotyping results in a single reaction well. IntelliQube provides cost savings through miniaturized PCR reaction volumes, shorter thermal cycling times, and multiplex reactions without compromising data quality.

This application note demonstrates the sensitivity, selectivity and reproducibility of solid phase Chromatrap®, as an assay for Chromatin IP from low cell numbers.

In this application note we show that the PHERAstar FS reader enables roGFP2-based measurements in mammalian cell monolayers grown in 96-well imaging plates.

This application note shows the methodology for viewing and evaluating captured cells on screen.