Latest App Notes & Case Studies

Download this app note to discover how Visium Spatial Gene Expression can help verify and refine traditional pathologist-led analysis as well as characterize spatial gene expression patterns of known prostate cancer markers plus much more.

Download this app note to discover a workflow that can detect SARS-CoV-2 RNA from challenging sample matrices and be used for the extraction and detection of other pathogens.

It takes approximately seven years to diagnose a patient with a rare disease. With NEW CentoXome®, this doesn’t have to be the case.

Fragment analysis of nucleic acids is an essential, well-known molecular biology tool used in many different research areas. Applications such as cloning, gene editing and fragment length analysis rely on quality control checks to assess the nucleic acid size at the beginning or middle of the workflow to ensure successful end results.

Download this app note to discover how to distinguish tumor versus normal cells in a heterogeneous sample, reconstruct cell type–specific gene regulatory network
and confirm PAX5 as a critical regulator specific to tumor B cells.

Download this compendium to discover tips and tricks for ultrafiltration including how to desalt samples, concentrate samples and recover low-concentrated samples.

Download this app note to discover a surveillance assay that rill remain effective as new variants emerge whilst offering high sensitivity and capture efficiency.

Download this app note to discover a method that includes a new cooling feature which is an efficient way to maintain nucleic acid integrity post-extraction that does not vary in its ability to elute the sample extracts into tubes for biobanking purposes.

Triple negative breast cancer (TNBC) is unresponsive to traditional hormone or targeted therapies and highly heterogeneous. Improved understanding of the biological underpinnings and cell-type composition of TNBC is critical to developing novel targeted treatment options.

Developing a thorough understanding of a gene’s contribution to a particular phenotype is problematic when the protein has an extended half-life or the phenotype under study requires days to materialize. Under these circumstances, reagents that induce long-term gene silencing are needed to sufficiently deplete internal cellular stores for extended periods of time.