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Detecting Systemic Interindividual Epigenetic Variation

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Studying DNA methylation at regions showing systemic interindividual variation in CpG methylation can provide researchers with insights into disease-associated epigenetic variation and its role in pathologies. Hence, cost-effective sequencing is essential for our advancement and understanding of epigenetic epidemiology. 

Discover how target-capture bisulfite sequencing methods now allow researchers to study epigenetic variation using easily biopsied blood samples.

Download this application note to learn more about:

  • Tools to analyze correlated regions of systemic interindividual epigenetic variation – CoRSIVs 
  • Optimizing target-capture bisulfite sequencing workflows
  • Deep bisulfite sequencing at costs competitive with methylation arrays  

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