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Genomic DNA Extractions Compared With the Agilent Femto Pulse System

Large-insert libraries require specific quality conditions of the starting genomic DNA (gDNA) material for successful outcomes. Physical, enzymatic and chemical shearing of gDNA into smaller fragments can occur at many different points during extraction and handling of gDNA. Therefore, accurate and reliable assessment of gDNA quality is essential for the success of these downstream sequencing processes.

Download this app note to discover a system that can: 

  • Replace overnight pulsed-field gel electrophoresis analysis of gDNA in only 70 minutes
  • Save sample material
  • Distinguish size distribution between similarly sized gDNA samples