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Preclinical Quantification of Trastuzumab in Rat Plasma

In quantifying therapeutic peptides and proteins in biological matrices, traditional ELISA-only based techniques can suffer from high variability, narrow dynamic range, problems with selectivity and typically cannot use internal standards.

Download this app note to learn how immunoaffinity-high resolution accurate mass assay: 

  • Has increased selectivity and sensitivity
  • Displays excellent robustness, reproducibility and dynamic range
  • Enables the confirmation of both in vitro and in vivo peptide modifications