truCOLLECT® Solution: High-Fidelity Genomic DNA Extraction from Decentralized, Dry-Stabilized Whole Blood for Biomarker Identification
Engineered specifically to address the operational gaps typically faced in decentralized testing, the Covaris truCOLLECT
Whole Blood Collection Kit, combined with AFA extraction technology, presents a robust and reliable integrated solution. As demonstrated by the extensive performance evaluation conducted by Ambry Genetics, the truCOLLECT Solution enables the reliable self-collection of 50 μL of capillary blood, which is immediately stabilized in a proprietary active-desiccation format and rapidly processed upon arrival using the Covaris R230 Focused-ultrasonicator. By combining this patient-centric sampling with automated precision, the truCOLLECT Solution yields superior HMW gDNA that provides genomic fidelity comparable to traditional phlebotomy. Characterized by seamless NGS pipeline integration, including 100% library preparation success, 99.9% clinical variant concordance, and confirmed compatibility across Sanger, MLPA, and array platforms, the system effectively
mitigates current operational inefficiencies. By eliminating cold-chain logistics, the truCOLLECT Solution enables laboratories to scale population genomics, and precision oncology initiatives efficiently and cost-effectively.