Your Guide to mAb Variants

Antibody-based derivatives have received increased attention as therapeutics in biopharmaceutical development because of their unique capacity to engage multiple molecular targets, engage immune effector cells or even penetrate tissues previously inaccessible to conventional mAbs. These therapeutics can be more complex and their development requires increased attention to ensure safety and efficacy.

Discover how SCIEX solutions can deliver the sensitivity and separation resolution needed to distinguish molecules with minor structural differences at low concentrations.

Access this info kit to learn more about:

• How capillary electrophoresis (CE) methods can be used to improve the separation resolution and charge variant analysis of your mAb variants
• Comprehensive characterizations of a multi-specific antibody therapeutics as well as antibody-drug conjugate (ADC)
  
• Peptide mapping analysis of etanercept – a highly glycosylated dimeric fusion protein
• Technology that will help increase throughput for the characterization of bispecific antibodies on the subunit level