Accelerating Drug Discovery Through Synthetic Biology
In the drug discovery pipeline, there are several areas where the speed and accuracy of new synthetic biology tools are making a measurable difference in the ability to accelerate drug development while concurrently reducing expenses. In this article, we take a closer look at how synthetic biology can be harnessed to aid the discovery and development of drugs.
Troubleshooting the Development of New Gene Therapies
As a cutting-edge biopharmaceutical technology, there are multiple gene therapies now FDA approved; with hundreds more in clinical trials, we’re likely to see many more of these therapies on the market soon. However, to keep up with the rapid pace of clinical research, developers are working to streamline the manufacturing and quality control process to improve quality and lower the cost of bringing these important drugs to market.
Venturing Into the Dark Unknown of Metabolomics With Deep Learning
A continual pursuit of discovery has brought researchers to, arguably, one of the greatest challenges yet in modern science: the field of metabolomics.
Identifying and Addressing Bias in Drug Development: An Interview With Dr Namandje N. Bumpus
In this interview with Technology Networks, Namandje N. Bumpus, Ph.D, Associate Dean for Basic Research and Associate Professor of Medicine from Johns Hopkins discusses the presence of bias from bench to bedside, highlights how this can impact clinical success, and explores ways to address bias throughout the drug development process.
Genetic Study Suggests Pangolins May Possess an Evolutionary Advantage Against Coronaviruses
In most mammals, there are certain genes that can be likened to an "alarm system", informing an organism when foreign material such as a virus enters the body and triggering an immune response. A new study published in the journal Frontiers in Immunology suggests that pangolins, despite being mammals, lack two of the genes involved in such an alarm system.
Exploring Differences in Drug Response With Dr Namandjé N. Bumpus
For the same dose of the same drug, two individuals might experience very different effects. This variation in drug response can be impacted by several drug-specific, genetic, biological, and environmental factors, and the interplay between these factors. In this interview, Namandjé N. Bumpus, Ph.D., Associate Dean for Basic Research and Associate Professor of Medicine, from Johns Hopkins, elaborates on her work exploring the differences between people in relation to drug response.
Exploring the Ethics of Genetic Testing: Where Does Duty Begin and End?
What are the legal, professional and ethical, duties of researchers and clinicians in handling genetic testing and the knowledge that might be gained from it?
Exploring the Ethics of Genetic Testing: What Does Consent Mean?
We explore the intricacies of informed consent in genetic testing, including the role of secondary findings and genetic counseling.
Exploring the Ethics of Genetic Testing
In this series, we’ll explore some of the ethical issues of genetic testing, including those surrounding consent and confidentiality and the roles of the parties involved.
Post-it Note PhD
The #PostItNotePhD challenge asked scientists to summarize their PhD on a single post-it note. Here are a selection of Technology Networks' favorites.